The Mouse Anti Human CD3E Antibody from MyBioSource.com is a Mouse Monoclonal antibody to CD3E, and CD3e molecule. This antibody recognizes Human antigen. The Mouse Anti Human CD3E Antibody has been shown to work in the following applications: ELISA, and Western Blot.
Description
CD3-epsilonpolypeptide (CD3E) along with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, creates the T-cell receptor-CD3 complex. This complex has an imperative role in coupling antigen recognition to a number of intracellular signal-transduction pathways. The genes encoding the epsilon, gamma delta polypeptides are found in the same cluster on chromosome 11. The epsilon polypeptide plays a vital role in T-cell development. CD3E gene defects cause immunodeficiency. CD3E is also linked to a susceptibility to type I diabetes in women