The RUVBL1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to RUVBL1. This antibody recognizes Human antigen. The RUVBL1 Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
Possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity; hexamerization is thought to be critical for ATP hydrolysis and adjacent subunits in the ring-like structure contribute to the ATPase activity.Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription