The Anti-RANK Antibody from MyBioSource.com is a Polyclonal antibody to TNFRSF11A. This antibody recognizes Mouse antigen. The Anti-RANK Antibody has been shown to work in the following applications: ELISA, and Western Blot.
Description
Description: Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 11A(TNFRSF11A) detection. Tested with WB, ELISA in Mouse.
Background: Receptor Activator of Nuclear Factor kappa B (RANK), also known as TRANCE Receptor, is a type I membrane protein that is expressed on the surface of osteoclasts and is involved in their activation upon ligand binding. RANK is also expressed on dendritic cells and facilitates immune signaling.RANKL (Receptor Activator for Nuclear Factor kappa B Ligand) is found on the surface of stromal cells, osteoblasts, and T cells. By analysis of somatic cell and radiation hybrid panels, Anderson et al. (1997) mapped the RANK gene to 18q22.1