The Rabbit Anti-MRGPRX2 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Mrgprx2. This antibody recognizes Human antigen. The Rabbit Anti-MRGPRX2 Antibody has been shown to work in the following applications: ELISA, and Western Blot.
Description
MRGPRX2 is the orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca(2+) but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled