Rabbit Anti-Caspase 3, Cleaved Antibody MBS628492 from MyBioSource.com

Description

Caspase 3 is one of the key executioners of apoptosis. It is responsible either partially or totally for the proteolytic cleavage of many key proteins such as the nuclear enzyme poly (ADP-ribose) polymerase (PARP). Activation of caspase 3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 subunits. Cleavage of caspase 3 requires aspartic acid at the P1 position

Product Specs
ItemRabbit Anti-Caspase 3, Cleaved Antibody
CompanyMyBioSource.com
Price $500.00Supplier Page View Company Product Page
Catalog NumberMBS628492
Quantity0.1 mL
ApplicationsELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Immunofluorescence (IF)
Conjugate/TagUnconjugated
FormatSupplied as liquid in 10mM HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol
PurityAffinity Purified
Purified by Protein A and immunoaffinity chromatography
ReactivityHuman, Monkey, Mouse, Rat
TargetCaspase 3, Cleaved
IsotypeIgG
HostRabbit
ImmunogenRecognizes cleaved human Caspase 3 (Asp175). Detects endogenous levels of the large fragment (17/19kD) of activated caspase-3 resulting from cleavage adjacent to Asp175. Does not recognize full length caspase-3 or other cleaved caspases. Detects non-specific caspase sunstrates by Western Blot
ClonalityPolyclonal