The Rabbit Anti-MAPRE1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to MAPRE1. This antibody recognizes Human, and Mouse antigen. The Rabbit Anti-MAPRE1 Antibody has been shown to work in the following applications: ELISA, Flow Cytometry, Immunohistochemistry, and Western Blot.
Description
The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family