The Mouse Anti Human HTRA2 Clone PAT3F9AT Antibody from MyBioSource.com is a Mouse Monoclonal antibody. This antibody recognizes Human antigen. The Mouse Anti Human HTRA2 Clone PAT3F9AT Antibody has been shown to work in the following applications: ELISA, Immunocytochemistry, Immunofluorescence, and Western Blot.
Description
HtrA2 also called Omi is a mammalian serine protease at high temperatures and has a chaperone activity at low temperature. The full-length HtrA2 is synthesized as a precursor protein and then targeted to the mitochondria where it is matured by the removal of N-terminal 133 residues. Mature HtrA2 consists of a putative transmembrane domain; an inhibitor of apoptosis protein (IAP)-binding motif; a single C-terminal PDZ domain that mediates protein-protein interactions. Recently, HtrA2 has known to contribute both to caspase-dependent and caspase-independent cell death