The Rabbit Anti-TSH Receptor / TSHR Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to TSHR. This antibody recognizes Human, Canine, Guinea Pig, Horse, Non-Human Primate, Porcine, and Other Mammalian antigen. The Rabbit Anti-TSH Receptor / TSHR Antibody has been shown to work in the following applications: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
Thyrotropin Receptor, a Glycoprotein Hormone Receptor, plays a central role in controlling thyroid cell metabolism. The TSH receptor can interact with both TSH and autoantibodies against the TSH receptor (thyroid-stimulating immunoglobulins, TSI). Mutations in the receptor are the cause for hyperthyroidism such as gestational hyperthyroidism (hypersensitivity to chorionic gonadotropin) and Grave's disease (autoimmune hyperthyroidism)