Phospho-Histone H3 (Ser10) (D7N8E) XP ® Rabbit mAb 53348S from Cell Signaling Technology

Product Specs
ItemPhospho-Histone H3 (Ser10) (D7N8E) XP ® Rabbit mAb
CompanyCell Signaling Technology
Price $431.00 Inquire
Catalog Number53348S
Molecular Weight17
Research AreaChromatin Regulation / Nuclear Function
ReactivityHu, Ms, Rt, Mk
ClonalityMonoclonal
NCBI Gene AliasesH3/A, H3C10, H3C11, H3C12, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8, H3FA, HIST1H3A
NCBI Full Gene NameH3 clustered histone 1
ApplicationsWB, FCM, ICC, IF, IHC, IHC-p, IP, ChIP
HostRabbit
ModificationsH3 (Ser10) phosphate
TargetH3 (Ser10) phosphate
Quantity100 µl

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Website: http://www.cellsignal.com/

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(1) Super-Multiplexed Label-Free Raman Imaging Uncovers Novel Testicular Metabolic Couplings for Residual Body and Spermatogonial DifferentiationAdv Sci (Weinh)July 21, 2026Jiaxin Li, Xia Chen, Yujuan Qi, Chen Qiao, Qiuru Huang, Dan Zhao, Weiyi Qian, Li Di, Yi Shi, Xiangqi Hu, et al.(DSHB, 1:50), mouse anti‐FasIII (DSHB, 1:50), rabbit anti‐dpERK (#4370, CST, 1:200), rabbit anti‐PH3 (#53348, CST, 1:600), rabbit anti‐cleaved Caspase‐3 (#9664, CST, 1:200), and rabbit anti‐TOM20 (#42406, CST,

(2) The WEE1 inhibitor azenosertib broadly enhances efficacy of antibody-drug conjugates with topoisomerase I and microtubule inhibitor payloadsiScienceJuly 17, 2026Xiao Guo, Doris Kim, Olivier Harismendy, Erika Cabrera, Heekyung Chung, Funda Meric-Bernstam, Mark R. Lackner, Catherine Lee, Jianhui MaAB_211800 Rabbit monoclonal anti-Phospho-Histone H3 (Ser10) (D7N8E),Cell Signaling Technology,Cat# 53348S; RRID: AB_2799431 Rabbit monoclonal anti-Phospho Chk1 (Ser345) (133D3),Cell Signaling Technology,Cat#

(3) Partial epithelial-to-mesenchymal transition mediates profound gap closure through growth and fluidizationbioRxivJuly 15, 2026Han Jiang, Chaozhen Wei, Pengbo Wang, Jaivarsini Johnson, Nonthakorn Olaranont, Yifan Gu, Feiyang Chen, Jian Xu, Qi Wen, Min Wu, et al.primary antibodies: anti-YAP (Abcam, sc-101199), anti-Phospho-Histone H3 (Cell Signaling Technology, 53348T), and anti–Golgin-97 (Invitrogen, A21270). For immunolabeling, donkey-anti rabbit Alexa Fluor 555 and

(4) VLX1570 suppresses neuroblastoma growth through inhibition of PCNA-associated proliferative signaling and potentiates cisplatin antitumor activityFront PharmacolJuly 15, 2026Wei-Hsun Yang, Chong-Sun Khoi, Kuan-Lin Kuo, Po-Ming Chow, Chen-Hsun Hsu, Yi-Ju Kao, Wei-Chou Lin, Shang-Jen Chang, Shih-Ming Liao, Felicia Tai, et al.cleaved caspase-7 (#8438), cleaved PARP (#9541), Bcl-2 (#15071), PCNA (#13110), phospho-histone H3 (#53348), and phospho-histone H2A.X (Ser139) (#9718) (all from Cell Signaling Technology, Danvers, MA, USA);

(5) Transcriptomics of S3 segment in mice: response to type 1 diabetes, SGLT1/2 inhibition, or GLP1 receptor agonismAmerican Journal of Physiology-Renal PhysiologyJuly 1, 2026Young Chul Kim, Chen Meng, Sadhana Kanoo, Scott Thomson, Anil Karihaloo, Volker Vallonincubated with anti-phospho-Ser10 Histone H3 rabbit monoclonal antibody (1:1,500 in 5% BSA in TBST, cat# 53348, Cell Signaling Technology, USA) for overnight at 4°C. After wash with TBST 3 times, the sections were

(6) SCP4 dephosphorylates mitotic histone H3 to maintain chromosome stabilityEMBO ReportsJune 19, 2026Yupiao Zheng, Zhengmao Zhang, Qi Wang, Jin Cao, Yang Li, Tingbo Liang, Xin-Hua Feng, Xia Lin(CHN).,A19524,1:50000 Anti-Myc-Tag,Cell Signaling Technology,2276,1:1000 Anti-phospho-Histone H3 (Ser10),Cell Signaling Technology,53348,1:500 Anti-phospho-Histone H3 (Ser28),Cell Signaling Technology,9713,1:1000 Anti-phospho-Histone H3 (Thr3

(7) Hsp70 is phosphorylated in a conserved response to DNA damage and contributes to cell cycle controlElifeMay 27, 2026Thomas Moss, Alexandra Wooldredge, Koustav Bhakta, Matthew Cronin, Jason E Gestwicki, Shaeri Mukherjee,Santa Cruz Biotechnology,sc-245,WB (1:500) Antibody,"Anti-phospho-histone-H3 (S10) (rabbit, monoclonal)",Cell Signaling Technology,53348S,WB (1:1000) Antibody,"Anti-cyclin E (mouse, monoclonal)",Santa Cruz Biotechnology,sc-247,WB (1:1000) Antibody,"Anti-CDT1

(8) DiMeLo-cito: a one-tube protocol for mapping protein-DNA interactions reveals CTCF bookmarking in mitosisbioRxivApril 11, 2026Nathan Gamarra, Cy Chittenden, Kousik Sundararajan, Jacob P. Schwartz, Sofia Lundqvist, Denise Robles, Oberon Dixon-Luinenburg, Jeremy Marcus, Annie Maslan, J. Matthew Franklin, et al.in this study were Rabbit anti-CTCF (Abcam) Mouse anti-CTCF (Thermo 1D11) Rabbit anti-H3s10ph (CST #53348) Rabbit Igg control(ab37415) and Mouse IgG Control (ab37355). DNA Extraction and Agilent Femto Pulse

(9) Novel Triazoloquinoxaline-Based Tubulin Polymerization Inhibitor Induces Necroptosis and Significantly Inhibits Metastatic Melanoma Tumor GrowthJournal of Medicinal ChemistryMarch 26, 2026Christopher J. Clark, Shelby N. Waddell, Garrett E. Tessmer, Carl B. Womack, Yang Xie, Brittney D. Williams, Meirola A. Endraws, Cole T. Huddleston, Keiluhn D. Pulis, Joshua Thammathong, et al.Chemidoc MP instrument. The antibodies used were: GAPDH-HRP (Cell Signaling, 8884), p–S10-H3 (Cell Signaling, 53348), and CYCLIN B1 (Cell Signaling, 4138). 4.3.7. Western Blot. A375/TxR cells were plated in 6-well

(10) Tri-Ortho-Cresyl Phosphate Inhibits Proliferation of Mouse Germ Cells by Activating Endoplasmic Reticulum Stress and Suppressing NTE ActivityToxicsMarch 25, 2026Dan Yang, Di Zhang, Xiao-Hua Song, Xiang-Dong Libelow. 2.2. Antibodies Antibodies against GRP78 (#3177), CHOP (#2895), BrdU (#5292), Phospho-H3 (Ser10) (#53348), and PCNA (D3H8P) were purchased from Cell Signaling Technology (Boston, MA, USA). Antibody against

(11) A cell cycle-dependent transition of acetylation to phosphorylation regulates timely centrosome maturationNat CommunMarch 20, 2026Jimin Li, Jianqiang Liang, Guifang Chen, Xuejie Wang, Yanyan Wang, Jingfei Zhan, Yunjing Guo, Jiadong Wang, Xuefeng Chen(Cell Signaling Technology, 9441, 1:1000 for WB; Immunechem, ICP0380, 1:500 for WB), anti-H3pS10(Cell Signaling Technology, 53348, 1:1000 for WB). The rabbit polyclonal phosphor-specific or acetyl-specific antibodies (anti-pT529-RNF40,

(12) Microcephaly-associated protein WDR62 supports purine metabolism by interacting with co-chaperone BAG2The EMBO JournalMarch 5, 2026Matthew J Morris, Yvonne Y Yeap, Jonathon R Edwards, Chi Chen, Annalisa Paolino, Sebastian G B Furness, S Sean Millard, Julia K Pagan, Laura R Fenlon, Dominic C H Ngmonoclonal),Abcam,ab2787 HSP90 (rabbit polyclonal),Abcam,ab13495 PH3 (rabbit monoclonal),Cell Signaling Technology,53348 TBR2 (sheep polyclonal),Invitrogen,PA5-47818 GFP (chicken polyclonal),Abcam,ab13970 Ki67 (mouse monoclonal),BD

(13) Duox-driven ROS release by glia promotes regeneration in the adult Drosophila brainEMBO ReportsFebruary 10, 2026Carolina S Alves, Anabel R Simões, Beatriz Gil Ferreira, Marta Neto, Carmo C Soares, Andreia Augusto, Christa Rhinerof the tissue. The primary antibodies used were Phospho-Histone H3 (Ser10) (D7N8E) XP® rabbit mAb #53348, Cell Signaling (1:50); anti-Repo (ms) (1:20) and anti-Elav (ms) (1:50) (DSHB). For PH3 staining (Cell

(14) Countervailing effects of cyclin isoforms A and B during mitosisbioRxivFebruary 2, 2026Shrea Bural, Duane A. Comptonab185622), GAPDH (1:1000; Santa Cruz Biotechnology; sc-365062), H3pS10 (1:1000; Cell Signaling Technology: #53348). Secondary antibodies for Western blotting are IRDye 680RD Goat anti-Mouse (1:10,000; #926-68070; LI-COR),

(15) DNA damage induced by HIV-1 Vpr triggers epigenetic remodeling and transcriptional programs to enhance virus transcription and latency reactivationPLoS BiolFebruary 2, 2026Nicholas Saladino, Emily Leavitt, Hoi Tong Wong, Jae-Hoon Ji, Diako Ebrahimi, Daniel J. SalamangoCell Signaling 34156), total H3 (1:1,000, Cell Signaling 4499), phospho-histone H3S10 (1:1,000, Cell Signaling 53348), acetyl-histone H3K9 (1:1,000, Cell Signaling 9649), tri-methyl-histone H3K9 (1:1,000, Cell Signaling

(16) The fluoropyrimidine polymer CF10 synergizes with 5-ethynyl-2′-deoxyuridine by promoting telomere attrition and mitotic catastropheNAR Molecular MedicineJanuary 23, 2026Upasana Das, Akanksha Behl, William H Gmeiner66% ethanol. Cells were stained for pH3 using anti-phospho-histone H3 Ab (Cell Signaling, Cat. No. 53348T) and secondary anti-rabbit IgG Fab2 Ab conjugated with Alexa-488 (Cell Signaling, Cat. No. 4412S). Cellular

(17) Disrupted autophagy overactivates TBK1 and results in mitotic defects promoting chromosomal instabilityAutophagyJanuary 22, 2026Swagatika Paul, Porter L. Tomsick, Julia P. Milner, Sahitya Ranjan Biswas, Samantha Brindley, Nicole DeFoor, Leila Zavar, Grace Wright, Yairis Soto, Alicia M. Pickrellab81292), H2AX (Cell Signaling Technology, 80312T), and p-Histone H3 (S10) (Cell Signaling Technology, 53348S). Secondary antibodies used for this study: peroxidase conjugated goat anti-mouse light chain specific

(18) Multi-omic analysis of human PHACTR1 signaling networksCommunications BiologyJanuary 19, 2026Kathryn Wolhuter, Lijiang Ma, Nicole S. Bryce, Osvaldo Contreras, Natalie Mellett, Ling Zhong, Chris Thekkedam, Siiri E. Iismaa, Corey Giles, Richard P. Harvey, et al.following all from Cell Signaling: CDT1 (#8064), Thymidine Kinase 1 (#28755), Phospho-Histone H3 (Ser10, #53348), Cyclin A2 (#91500), Cyclin B1 (#12231), Cyclin E1 (#20808), Phospho-cdc2 (Tyr15, #4539), Tom20 (#42406),

(19) Long-term memory in epithelia: transient IFNγ exposure drives stable repression of TFF1 in gastric epithelial cells via epigenetic changesFrontiers in ImmunologyJanuary 7, 2026Antonia Voli, Daniela Eletto, Fatima Maria Mentucci, Chiara Centrella, Martina Pannetta, Francesco Boccellato, Alfonso Finizio, Silvana Morello, Caterina Giraulo, Amalia Porta, et al.immunoprecipitated with anti-C/EBPβ antibody (Cell Signaling, #90081S, USA), anti-H3S10ph antibody (Cell Signaling, 53348, USA), anti-H3K27me3 antibody (Abcam, ab6002) or anti-H3K9ac antibody (Abcam, ab10812) respectively

(20) Imaginal discs produce neuropeptide-like precursor 1 to alleviate ER stress in response to warm temperaturesCommunications BiologyDecember 16, 2025Il-Ju Kim, Do-Hyoung Kim, Young-Joon KimCas3 (1:400; Cell Signaling, 9661 T), rabbit anti-phospho-histone H3 (Ser10) (1:500; Cell Signaling, 53348S), guinea pig anti-ATF4 (1: 500; gift from Min-Ji Kang), Alexa 488-conjugated goat anti-mouse (1:1000;

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Phospho-Histone H3 (Ser10) (D7N8E) XP ® Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Phospho-Histone H3 (Ser10) (D7N8E) XP ® Rabbit mAb from Cell Signaling Technology

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