Anti-p63 antibody [N2C1], Internal GTX102425 from GeneTex

Product Specs
ItemAnti-p63 antibody [N2C1], Internal
CompanyGeneTex
Price $169.00Supplier Page
Catalog NumberGTX102425
Quantity25 µl
Conjugate/TagUnconjugated
ApplicationsWB, ICC/IF, IHC-P, IHC-Fr, IP, PLA
FormatPBS, 20% Glycerol, 0.025% ProClin 300
Concentration0.62mg/ml
ReactivityHuman, Mouse, Rat, Cat, Dog
HostRabbit
PurityPurified by antigen-affinity chromatography
Targetp63
IsotypeIgG
Molecular Weight77
ClonalityPolyclonal
ImmunogenRecombinant protein encompassing a sequence within the center region of human p63. The exact sequence is proprietary
Antibody TypePrimary Antibodies
NCBI Full Gene Nametumor protein p63
NCBI Gene AliasesEEC3, TP53CP, p63, tumor protein p63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L, SHFM4, B(p51B), TP53L, RHS, NBP, B(p51A), AIS, p51, p53CP, TP73L, p73L, LMS, KET, OFC8, p73H, p40
Research AreaCancer
Gene NameTP63

Questions and Answers

Can this antibody be used for immunofluorescence in canine tissues?

Yes, the Anti-p63 antibody [N2C1] has been shown to work in immunofluorescence applications for canine tissues, as demonstrated in a study where it was used to evaluate the expression of p63 in canine corneal organoids ().

Is the Anti-p63 antibody effective for detecting p63 in mouse models?

The Anti-p63 antibody [N2C1] has been utilized in various studies involving mouse models, including its application in immunohistochemistry and immunofluorescence to assess p63 expression in different contexts, such as in bladder cancer research ().

What is the recommended dilution for using this antibody in immunohistochemistry?

The recommended dilution for the Anti-p63 antibody [N2C1] in immunohistochemistry is 1:300, as indicated in multiple studies that employed this antibody for detecting p63 in various tissue types (, ).

Does this antibody have any applications in cancer research?

Yes, the Anti-p63 antibody [N2C1] has been cited in several cancer research studies, including its role in understanding the mechanisms of prostate cancer progression and its involvement in the differentiation of bladder cancer cells (, ).

GeneTex

GeneTex, Inc. 2456 Alton Parkway

Irvine, California 92606

United States

Phone: 1-877-GeneTex (436-3839) or 949-553-1900
Fax: 949-309-2888

Company Profile

Website: http://www.genetex.com

(1) VSIG10L is a major determinant of esophageal homeostasis and inherited predisposition to Barrett’s esophagusNature CommunicationsJanuary 29, 2026Durgadevi Ravillah, Salendra Singh, Ramachandra M. Katabathula, Adam M. Kresak, Bhavatharini Udhayakumar, Rajesh Gupta, Wendy Brock, Yosuke Mitani, Vaibhav Jain, Emily Hocke, et al.14-4758-82, 1:5000 dilution), Sox9 (Abcam; cat. no. ab185230, 1:1000 dilution), p63 (GeneTex, cat. no. GTX102425, 1:100 dilution), or CK7 (Abcam, cat. no. ab181598, 1:50,000) overnight at 4 °C. Detection of antibodies

(2) Deciphering the dynamic single-cell transcriptional landscape in the ocular surface ectoderm differentiation systemLife MedOctober 1, 2024Zhang C, Lin Z, Yu Y, Wu S, Huang H, Huang Y, Liu J, Mo K, Tan J, Han Z, et al.Scientific, USA). The primary antibodies used for immunofluorescence are as follows: anti-TP63 (GeneTex, # GTX102425, 1:200), anti-PAX6 (BioLegend, #939802, anti-KRT3 (Abcam, #ab68260, 1:200), anti-KRT4 (GeneTex, #GTX112211,

(3) Rosiglitazone and trametinib exhibit potent anti-tumor activity in a mouse model of muscle invasive bladder cancerNature communicationsAugust 2, 2024Plumber SA, Tate T, Al-Ahmadie H, Chen X, Choi W, Basar M, Lu C, Viny A, Batourina E, Li J, et al.Anti- FOXA1,Seven Hills Bioreagents,Cat# WMAB-2F83,2F83,1:1000 Rabbit Polyclonal Anti-p63,GeneTex,Cat#GTX102425,N/A,1:300 Goat Polyclonal Anti-p63,R&D Systems,Cat#AF1916,N/A,1:200 Rat Monoclonal Anti-CD45,BD Bioscience,Cat#550539,30F11,1:100 Rabbit

(4) The mechano-chemical circuit in fibroblasts and dendritic cells drives basal cell proliferation in psoriasisCell reportsJuly 23, 2024Jiang J, Shao X, Liu W, Wang M, Li Q, Wang M, Xiao Y, Li K, Liang H, Wang N, et al.

(5) A scalable and cGMP-compatible autologous organotypic cell therapy for Dystrophic Epidermolysis BullosaNature communicationsJuly 11, 2024Neumayer G, Torkelson JL, Li S, McCarthy K, Zhen HH, Vangipuram M, Mader MM, Gebeyehu G, Jaouni TM, Jacków-Malinowska J, et al.

(6) LncRNA CTBP1-AS inhibits TP63-mediated activation of S100A14 during prostate cancer progressionCancer scienceMay 1, 2024Wu G, Dong Z, Dong Y, Chen Y, Zhu H, Ding D, Cui Y, Wang Y, Xu Y, Chen H.another part of the extract was reacted with protein A/G magnetic bead‐conjugated anti‐TP63 (1:100, GTX102425, GeneTex Inc., San Antonio, TX, USA) or IgG (1:100, ab172730, Abcam) at 4°C overnight. The magnetic‐protein

(7) Reciprocal inhibition between TP63 and STAT1 regulates anti-tumor immune response through interferon-γ signaling in squamous cancerNature communicationsMarch 20, 2024Jiang Y, Zheng Y, Zhang YW, Kong S, Dong J, Wang F, Ziman B, Gery S, Hao JJ, Zhou D, et al.in PBS. Primary antibodies including CD8α (1:300; 70306, Cell Signaling Technology) and p63 (1:100; GTX102425, GeneTex) were incubated overnight at 4 °C. The next day, the samples were incubated with fluorescence

(8) Viral airway injury promotes cell engraftment in an in vitro model of cystic fibrosis cell therapyAmerican journal of physiology. Lung cellular and molecular physiologyMarch 1, 2024Lee RE, Mascenik TM, Major SC, Galiger JR, Bulik-Sullivan E, Siesser PF, Lewis CA, Bear JE, Le Suer JA, Hawkins FJ, et al.

(9) Transcription factor Tcf21 modulates urinary bladder size and differentiationDevelopment, growth & differentiationFebruary 1, 2024Mann EA, Mogle MS, Park JS, Reddy P."Novus Biologicals, CO, USA" Uroplakin IIIa,1:100,SC‐15186,"Santa Cruz Biotechnology, CA, USA" p63,1:300,GTX102425,"GeneTex, CA, USA" Keratin 5,1:500,905501,"BioLegend, CA, USA" Keratin 14,1:250,906001,"BioLegend,

(10) Successful reconstruction of the rat ureter by a syngeneic collagen tube with a cardiomyocyte sheetRegenerative therapyDecember 1, 2023Yamamoto S, Matsui K, Kinoshita Y, Hiroshi Sasaki, Sekine H, Saito Y, Nakayama Y, Kume H, Kimura T, Yokoo T, et al.binding protein 3 (GATA3; AF2605, R&D systems, Minneapolis, MN, USA), anti-tumor protein 63 (TP63; GTX102425, GeneTex, Irvine, CA, USA), anti-alpha smooth muscle actin (αSMA; A2547, Sigma Aldrich, St. Louis, MO,

(11) Ahnak is required to balance calcium ion homeostasis and smooth muscle development in the urinary systemCell & bioscienceJune 12, 2023Lee JM, Lim TY, Oh SB, Lee SJ, Bae YS, Jung HS.

(12) Uropathogenic Escherichia coli infection-induced epithelial trained immunity impacts urinary tract disease outcomeNature microbiologyMay 1, 2023Russell SK, Harrison JK, Olson BS, Lee HJ, O'Brien VP, Xing X, Livny J, Yu L, Roberson EDO, Bomjan R, et al.mouse monoclonal anti-uroplakin 3a (Fitzgerald, 10R-U103a, 1:50), rabbit polyclonal anti-p63 (GeneTex, GTX102425, 1:1,000), rabbit monoclonal anti-K5 (Abcam, ab150074, 1:100) and mouse monoclonal anti-keratin 14 (Santa Cruz

(13) A scalable, GMP-compatible, autologous organotypic cell therapy for Dystrophic Epidermolysis BullosabioRxiv : the preprint server for biologyMarch 1, 2023Neumayer G, Torkelson JL, Li S, McCarthy K, Zhen HH, Vangipuram M, Jackow J, Rami A, Hansen C, Guo Z, et al.

(14) Contribution of Trp63(CreERT2)-labeled cells to alveolar regeneration is independent of tuft cellseLifeSeptember 21, 2022Huang H, Fang Y, Jiang M, Zhang Y, Biermann J, Melms JC, Danielsson JA, Yang Y, Qiang L, Liu J, et al.monoclonal),Abcam,ab17130,1:500 Antibody,Anti-Krt5(Rabbit polyclonal),Abcam,ab53121,1:500 Antibody,Anti-p63(Rabbit polyclonal),Genetex,GTX102425,1:200 Antibody,Anti-p63(Mouse monoclonal),Abcam,ab735,1:200 Antibody,Anti-Acetylated tubulin(Mouse

(15) Cis-regulatory chromatin loops analysis identifies GRHL3 as a master regulator of surface epithelium commitmentScience advancesJuly 15, 2022Huang H, Liu J, Li M, Guo H, Zhu J, Zhu L, Wu S, Mo K, Huang Y, Tan J, et al.KRT19 (Thermo Fisher Scientific, MS-1902-P; 1:1000), NANOG (GeneTex, GTX100863; 1:500), TP63 (GeneTex, GTX102425; 1:500), ADD2 (Proteintech, 14640-1-AP; 1:500), TUBB4A (Abcam, ab179509; 1:500), DSP (Proteintech, 25318-1-AP;

(16) Targeted deletion of TGFβ1 in basal keratinocytes causes profound defects in stratified squamous epithelia and aberrant melanocyte migrationDevelopmental biologyMay 1, 2022Chalmers FE, Dusold JE, Shaik JA, Walsh HA, Glick AB.,Cell Signaling Technologies,1:1000,2230 α-Loricrin,Rabbit,Biolegend,1:500,905103 "α-p63 (Internal, N2C1)",Rabbit,GeneTex,1:1000,GTX102425 α-ΔNp63,Rat,Biolegend,1:1000,699501 α-TAp63,Mouse,Biolegend,1:1000,938101 α-phospho- SMAD2 (S465/467)

(17) Human distal lung maps and lineage hierarchies reveal a bipotent progenitorNatureApril 1, 2022Kadur Lakshminarasimha Murthy P, Sontake V, Tata A, Kobayashi Y, Macadlo L, Okuda K, Conchola AS, Nakano S, Gregory S, Miller LA, et al.anti-UGRP1 (R&D systems, # AF3545, 1:500), Rat anti-CC10 (R&D, MAB4218, 1:500), Rabbit anti-p63 (Genetex, #GTX102425, 1:500), Mouse anti-p63 (Clone 4A4, a kind gift from Dr. Frank Mckeon, 1:20, originally described in

(18) Culture and characterization of canine and feline corneal epithelial organoids: A new tool for the study and treatment of corneal diseasesFrontiers in veterinary scienceJanuary 1, 2022Bedos L, Wickham H, Gabriel V, Zdyrski C, Allbaugh RA, Sahoo DK, Sebbag L, Mochel JP, Allenspach K.Confocal (Supplementary Figure 1) or Keyence BZ X-100 (Supplementary Figure 2) the next day. P63 (Ref. GTX102425, Genetex) was used in a concentration of 1:50 in a Citrate buffer. AQP1 (Ref. NBP1-84488, Novus Biologicals)

(19) PTEN expression and morphological patterns in prostatic adenocarcinomaHistopathologyDecember 1, 2021Spieker AJ, Gordetsky JB, Maris AS, Dehan LM, Denney JE, Arnold Egloff SA, Scarpato K, Barocas DA, Giannico GA.Leica-Bond Max immunostainer on 5-μm sections (PTEN, M3627; Dako, Carpinteria, CA, USA; 1:200, p63, GTX102425; Genetex, Irvine, CA, 1:100). We have previously established concordance of our in-house PTEN immunohistochemical

(20) Vaginal Squamous Cell Carcinoma Develops in Mice with Conditional Arid1a Loss and Gain of Oncogenic Kras Driven by Progesterone Receptor CreThe American journal of pathologyJuly 1, 2021Wang X, Praça MSL, Wendel JRH, Emerson RE, DeMayo FJ, Lydon JP, Hawkins SM.

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Anti-p63 antibody [N2C1], Internal

Anti-p63 antibody [N2C1], Internal

Anti-p63 antibody [N2C1], Internal

Anti-p63 antibody [N2C1], Internal from GeneTex

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Anti-p63 antibody [N2C1], Internal from GeneTex

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