Anti-Laminin 2 alpha antibody [4H8-2] ab11576 from Abcam

Product Specs
ItemAnti-Laminin 2 alpha antibody [4H8-2]
CompanyAbcam
Price Pricing Info Supplier Page View Company Product Page
Catalog Numberab11576
Domain/Region/Terminus8-2
Antibody TypePrimary
Clone4H8-2
ClonalityMonoclonal
IsotypeIgG1
Quantity25 UL
HostRat
ApplicationsImmunohistochemistry (Frozen sections)
Conjugate/TagUnconjugated
Concentration2.2 mg/ml
Research AreaNeuroscience
Gene NameLAMA2
ReactivityMouse
TargetLaminin 2 alpha

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(1) Electrical impedance myography detects dystrophin-related muscle changes in mdx miceSkeletal MuscleNovember 18, 2023Tetsuaki Hiyoshi, Fuqiang Zhao, Rina Baba, Takeshi Hirakawa, Ryosuke Kuboki, Kazunori Suzuki, Yoshiro Tomimatsu, Patricio O’Donnell, Steve Han, Neta Zach, et al.thick) were stained for the cell membrane with a rat monoclonal anti-laminin 2 alpha antibody (4H8-2, ab11576, dilution 1:1000; Abcam, Cambridge, UK) for 30 min at room temperature. The cell membrane of the muscle

(2) A cellular and molecular spatial atlas of dystrophic muscleProceedings of the National Academy of Sciences of the United States of AmericaJuly 18, 2023Stec MJ, Su Q, Adler C, Zhang L, Golann DR, Khan NP, Panagis L, Villalta SA, Ni M, Wei Y, et al.software (Indica Labs). Primary antibodies were as follows: laminin (Sigma-Aldrich, L9393 & 1:500; Abcam, ab11576), F-actin (1:500; Invitrogen, A22287), collagen I (Abcam, ab270993), F4/80 (Abcam, ab6640), perilipin

(3) In-Frame Deletion of Dystrophin Exons 8–50 Results in DMD PhenotypeInternational Journal of Molecular SciencesMay 23, 2023Tatiana V. Egorova, Ivan I. Galkin, Oleg A. Velyaev, Svetlana G. Vassilieva, Irina M. Savchenko, Vyacheslav A. Loginov, Marina A. Dzhenkova, Diana S. Korshunova, Olga S. Kozlova, Dmitry N. Ivankov, et al.(ab189254, 1:2000; Abcam), and co-stained with rat monoclonal antibodies raised against laminin 2α [4H8-2] (ab11576, 1:250; Abcam) at 4 °C overnight. Antibodies were diluted in a 3% BSA blocking buffer. The following

(4) Active Remodeling of Capillary Endothelium via Cancer Cell-Derived MMP9 Promotes Metastatic Brain ColonizationCancer researchApril 14, 2023Karreman MA, Bauer AT, Solecki G, Berghoff AS, Mayer CD, Frey K, Hebach N, Feinauer MJ, Schieber NL, Tehranian C, et al.anti-Laminin (1:100, ab30320, Abcam, United Kingdom, RRID:AB_775970), anti-Laminin 2 alpha (1:200, ab11576, Abcam, United Kingdom, RRID:AB_298180), anti-MMP9 (1:100, ab38898, Abcam, United Kingdom, RRID:AB_776512),

(5) Myoscaffolds reveal laminin scarring is detrimental for stem cell function while sarcospan induces compensatory fibrosisnpj Regenerative MedicineMarch 15, 2023Kristen M. Stearns-Reider, Michael R. Hicks, Katherine G. Hammond, Joseph C. Reynolds, Alok Maity, Yerbol Z. Kurmangaliyev, Jesse Chin, Adam Z. Stieg, Nicholas A. Geisse, Sophia Hohlbauch, et al.Fitzgerald Industries), fibronectin (AB2413; 1:250; Abcam), laminin (L9393; 1:500; Sigma-Aldrich) and laminin alpha-2 (AB11576; 1:150; Abcam). Primary antibodies were detected by biotinylated anti-rabbit (BA-1000; 1:500; Vector Laboratories

(6) IRE1α arm of unfolded protein response in muscle-specific TGF-β signaling-mediated regulation of muscle cell immunological propertiesCellular & molecular biology lettersFebruary 27, 2023Xiao J, Huang J, Jian X, Wang H, Lan H, Liao Z, Gu R, Hu J, Liao H.50-0112-82), rabbit anti-mouse dystrophin (1:500, Bioss, bs-14477R), rat anti-mouse laminin (1:200, Abcam, ab11576), rabbit polyclonal anti-fast myosin muscle heavy chain (MyHC, 1:500, abcam, ab91506), rabbit anti-mouse

(7) The mini-IDLE 3D biomimetic culture assay enables interrogation of mechanisms governing muscle stem cell quiescence and niche repopulationeLifeDecember 20, 2022Erik Jacques, Yinni Kuang, Allison P Kann, Fabien Le Grand, Robert S Krauss, Penney M Gilbert#ab203254" Anti-M-cadherin,Mouse IgG1,1:250,"Santa-Cruz, #sc-81471" Anti-Laminin α-2,Rat,1:400,"Abcam, #ab11576" Anti-FoxO3a,Mouse IgG1,1:250,"Santa-Cruz, #sc-48348" Alexa Fluor 488 Anti-mouse IgG (H+L),Goat,1:500,"Invitrogen,

(8) p62/Sqstm1 rescue in muscle retards the progression of steatohepatitis in p62/Sqstm1-null mice fed a high-fat dietFrontiers in PhysiologyNovember 1, 2022Ikuru Miura, Kosuke Okada, Akiko Ishii, Eiji Warabi, Takahisa Watahiki, Keii To, Hitoshi Shimano, Shunichi Ariizumi, Junichi Shodaimmunofluorescent staining,Antibodies for immunofluorescent staining Antigen,Supplier,Catalog number,Dilution Laminin 2α,Abcam,ab11576,1:500 Slow myosin heavy chain,Abcam,ab234431,1:200 Antibodies for immunoblotting,Antibodies for immunoblotting

(9) Scalable macroporous hydrogels enhance stem cell treatment of volumetric muscle lossBiomaterialsNovember 1, 2022Eugenis I, Wu D, Hu C, Chiang G, Huang NF, Rando TA.ab182981, 1:500), CD68 (Invitrogen, FA-11, 1:250), CD206 (Proteintech, 18704–1-AP, 1:250), Laminin (Abcam, ab11576, 1:500), Neurofilament (Invitrogen, MA5–14981, 1:250), Alexa Fluor 594 Donkey anti-Rat (Invitrogen,

(10) Control of backbone chemistry and chirality boost oligonucleotide splice switching activityNucleic Acids ResearchJune 10, 2022Pachamuthu Kandasamy et al.(Abcam, Cat. No. ab15277, 1:400 diluent) and a monoclonal rat anti-laminin antibody (Abcam, Cat No. ab11576, 1:400 diluent) prepared in antibody dilution buffer (Invitrogen, Cat. No. 003218) overnight at +4°C.

(11) Bap1/SMN axis in Dpp4+ skeletal muscle mesenchymal cells regulates the neuromuscular systemJCI InsightMay 23, 2022Ji-Hoon Kim, Jong-Seol Kang, Kyusang Yoo, Jinguk Jeong, Inkuk Park, Jong Ho Park, Joonwoo Rhee, Shin Jeon, Young-Woo Jo, Sang-Hyeon Hann, et al.blocking buffer (5% goat and horse serum in PBS) and incubated overnight with rat anti-laminin (Abcam, ab11576, 1:2000 dilution) in blocking buffer at 4°C. After incubation, slides were washed with PBS 3 times and

(12) CPEB1 directs muscle stem cell activation by reprogramming the translational landscapeNature communicationsFebruary 17, 2022Zeng W, Yue L, Lam KSW, Zhang W, So WK, Tse EHY, Cheung TH.were Myod1 (Dako, Clone 5.8 A,1:500), Ki67 (Abcam, ab16667, 1:100), Pax7 (DSHB, 1:50), Laminin (Abcam, ab11576, 1:1,000), Syn4 (kind gift from Prof. Dawn Cornelison, 1:500), CPEB1 (Abcam, Ab73287, 1:500), pCPEB1

(13) Acute T2*-Weighted Magnetic Resonance Imaging Detectable Cerebral Thrombosis in a Rat Model of Subarachnoid HemorrhageTranslational Stroke ResearchFebruary 1, 2022Jingwei Zhang, Kang Peng, Fenghui Ye, Sravanthi Koduri, Ya Hua, Richard F. Keep, Guohua Xiwere rabbit anti-fibrinogen (1:200 dilution, ab34269, Abcam) and rat anti-laminin 2α (1:1200 dilution, ab11576, Abcam). The secondary Abs were Alexa Fluro 488-conjugated donkey anti-rat mAb (1:800 dilution, Invitrogen),

(14) Low immunogenicity of LNP allows repeated administrations of CRISPR-Cas9 mRNA into skeletal muscle in miceNature CommunicationsDecember 8, 2021Eriya Kenjo, Hiroyuki Hozumi, Yukimasa Makita, Kumiko A. Iwabuchi, Naoko Fujimoto, Satoru Matsumoto, Maya Kimura, Yuichiro Amano, Masataka Ifuku, Youichi Naoe, et al.anti-dystrophin (cat #ab15277, Abcam, Cambridge, UK) or 1000-fold diluted polyclonal anti-Laminin 2 alpha (cat #ab11576, Abcam, Cambridge, UK) for 2 h at room temperature or overnight at 4 °C and then reacted with goat anti-Rabbit IgG (H;L) antibody

(15) Simvastatin does not alleviate muscle pathology in a mouse model of Duchenne muscular dystrophySkeletal MuscleDecember 1, 2021Olga Mucha, Paulina Podkalicka, Katarzyna KazirÃ³d, Emilia Samborowska, JÃ³zef Dulak, Agnieszka ÅobodaAlexa Fluor 488 antibody, Thermo Fisher Scientific) with laminin α2 (rabbit anti-mouse antibody, Abcam, ab11576; secondary antibody: goat anti-rabbit Alexa Fluor 568) and showed as a percentage of necrotic fibers

(16) Gait disturbances and muscle dysfunction in fibroblast growth factor 2 knockout miceScientific ReportsDecember 1, 2021C. Homer-Bouthiette, L. Xiao, Marja M. Hurleyfor 10 min at room temperature. Samples were incubated with anti-laminin 2 alpha primary antibody (ab11576, Abcam, Cambridge, UK) or anti-F4/80 primary antibody (ab6640, Abcam, Cambridge, UK) in blocking solution

(17) Maintenance of type 2 glycolytic myofibers with age by Mib1-Actn3 axisNature CommunicationsDecember 1, 2021Ji-Yun Seo et al.dilution), or mouse anti-MyHC type 2x (DSHB, 6H-1, 1:5 dilution) in addition to rat anti-laminin (Abcam, ab11576, 1:2000 dilution) in 5% BSA blocking buffer. After washes in PBS, sections were incubated for 1 h with

(18) Targeting microRNA-mediated gene repression limits adipogenic conversion of skeletal muscle mesenchymal stromal cellsCell stem cellJuly 1, 2021Wosczyna MN, Perez Carbajal EE, Wagner MW, Paredes S, Konishi CT, Liu L, Wang TT, Walsh RA, Gan Q, Morrissey CS, et al.,Santa Cruz,Clone#:E-8 Cat# sc-7273RRID: AB_628115 Laminin 2 alpha monoclonal antibody,Abcam,"Clone#: 4H8-2Cat# ab11576, RRID: AB_298180" Cleaved Caspase-3 (Asp175) polyclonal antibody,Cell Signaling,Cat# 9661S; RRID:AB_2341188 Sp7/Osterix

(19) Induced endothelial cells from peripheral arterial disease patients and neonatal fibroblasts have comparable angiogenic propertiesPloS oneJanuary 1, 2021Hywood JD, Sadeghipour S, Clayton ZE, Yuan J, Stubbs C, Wong JWT, Cooke JP, Patel S.frozen in OCT, with 5 μm sections of these samples stained with anti-CD31, anti-laminin (ab25644 and ab11576 respectively, Abcam plc. 330 Science Park, Cambridge CB4, UK) and anti-α smooth muscle actin (F3777,

(20) Temporal inhibition of autophagy reveals segmental reversal of ageing with increased cancer riskNature CommunicationsDecember 1, 2020Liam D. Cassidy et al.Mouse Blocking Reagent (MKB-2213) according to manufacturer’s instructions and anti-LAMININ (Abcam, ab11576, 1:1000). Bone marrow transplantation Atg5i mice were backcrossed 11 times to C57BL/6. At 2-month

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2/23/2017Laminin Alpha 2 Antibody Maria PearceLaminin 2 alpha antibody is an extracellular protein that plays an important role in the kidney's basement membrane. This antibody helps to identify protein that leads to abnormalities with the ... Read Review

Anti-Laminin 2 alpha antibody [4H8-2] from Abcam

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Anti-Laminin 2 alpha antibody [4H8-2] from Abcam

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