HPLC Detectors

An HPLC detector is a crucial component of the high-performance liquid chromatography system, as it is responsible for identifying the analytes traveling through the column. There are different types of detectors a researcher could use, which vary depending on the chemical and physical properties of the eluting samples. This catalog lists a variety of HPLC detectors from different manufacturers.

Types of HPLC Detectors

• Diode Array Detector - These are most commonly used to record the ultraviolet and visible (UV-vis) absorption spectra. An advantage of the diode array detector is the ability to select the best wavelength for analysis.
• Conductivity Detector - These detectors measure the ability to pass an electric current by recording electronic resistance. This can be used to determine the concentration of ionic compounds.
• Evaporative Light Scattering Detector - ELSDs provide comprehensive information about analytes, including measurement of particle size below a nanometer, molecular weight, and zeta potential.
• Refractive Index Detector - HPLC RI detectors are often used when analyzing substances with limited or no UV absorption, which can include alcohols, sugars, fatty acids, polymers, and carbohydrates.
• UV-Vis Detector - These detectors measure the absorption of light at different wavelengths. Single wavelength detectors measure absorption of a single wavelength, while variable wavelength detectors can measure multiple wavelengths, improving sensitivity.
• Fluorescence Detector - These detectors introduce excitation light at a particular wavelength and measure the intensity of the emitted light at another wavelength. They can be used to measure concentrations of analytes such as pharmaceuticals and other fluorescent compounds.