Functional genomics offers powerful tools to study immune function. Techniques such as single-cell RNA sequencing allow researchers to identify genes that influence immune cell development, activation, and response to pathogens. Multi-omics approaches combine genomic, transcriptomic, proteomic, and epigenomic data to reveal complex signaling pathways and interactions within immune cells. Overall, functional genomics enhances our ability to dissect immune system dynamics at a molecular level, driving advances in immunology research and clinical applications.
The two presentations in this webinar will demonstrate how large-scale biobank data and multi-omics resources can be leveraged to uncover novel genetic and molecular mechanisms that govern immune function in human populations.
Samira Asgari will explain how laboratory test data from large biobanks can be used to map the role of infectious disease–associated variants in immunity. By linking population-scale genetic data with immune phenotypes, her work reveals how functional genomic approaches can pinpoint connections between host genetics and disease susceptibility.
Maria Gutierrez-Arcelus will review a multi-omics resource of human B-cell activation that captures the dynamic behavior of disease-associated genes. This dataset provides a powerful lens into the cellular and molecular pathways that shape immune responses, offering new insights into immune regulation and dysfunction.
Register today to learn how these novel approaches are expanding the frontiers of immune system genomics.
Topics to be discussed in this webinar
- Utilization of large-scale biobanks to map infectious disease–associated genetic variants influencing immune function and disease susceptibility, with implications for other immune-mediated diseases.
- Application of population-scale genetic data linked with immune phenotypes to uncover connections between host genetics and immune responses.
- A comprehensive multi-omics resource detailing human B-cell activation and dynamic gene behavior associated with disease.
- Insights into cellular and molecular pathways shaping immune regulation and dysfunction through functional genomics and multi-omics approaches.