The ability to study biological systems and processes in three dimensions is revealing new insights into the mechanisms of disease and revolutionizing drug discovery and development. However, the use of these more advanced and predictive models is not without bottlenecks. Workflows can be demanding, often requiring 24/7 oversight, precise feeding schedules, and numerous time-consuming, error-prone, and repetitive procedures. All this hands-on time increases costs and variability and significantly delays results.
A new offering from Molecular Devices, a leading lab solutions provider focused on facilitating research and enhancing workflows, overcomes these hurdles. The CellXpress.ai™ Automated Cell Culture System brings a whole new standard to the paradigm of 3D biology, marrying artificial intelligence and automation to significantly streamline and scale even the most complex cell cultures. The CellXpress.ai cell culture system’s machine learning-assisted software standardizes development to deliver consistent, unbiased, and biologically relevant results at scale. Confidence in these results means you can make key decisions sooner, achieve milestones faster, and get to clinic earlier—all with lower attrition rates.
Designed by scientists for scientists, the CellXpress.ai cell culture system’s intuitive, easy-to-use “protocol wizard” interface helps users avoid complex scripting when building their workflows. A comprehensive event log confirms on-time feedings and critical task execution and is supplemented by detailed digital microscopy records. The CellXpress.ai cell culture system also easily identifies outliers at the well, plate, or experiment level to help detect sources of variability.
The instrument is flexible enough to support a multi-user environment with the ability to run several different protocols simultaneously. It is also scalable to accommodate over 100 plates in an experiment. The expansion ports allow additional instruments to be integrated for workflow flexibility, while a built-in incubator offers different capacity options to fit your workflow volume.
The CellXpress.ai cell culture system is also flexible, with the ability to streamline an array of workflows—including disease modeling, drug discovery and development, oncology, stem cell research, and toxicology—by automating cell imaging and analysis, handling cells in extracellular matrices, and feeding and passaging iPSCs, organoids, and spheroids. Integrated machine learning-enabled software includes built-in protocols for generating 2D as well as 3D models.
In short, the CellXpress.ai cell culture system reliably manages the entire cell journey, allowing your lab to access more biologically relevant models and ensure reproducibility at scale. It is a complete solution, standardizing maintenance, monitoring, and incubation, through imaging, analysis, and data processing. This transformative innovation—and the consistent, unbiased, and biologically relevant results it provides—will be a game-changer for any drug discovery and development lab.