Kinases are a class of enzymes that catalyze the transfer of phosphate groups, generally from high-energy molecules such as ATP to specific substrates. These enzymes play an important role in many metabolic pathways, especially in signal transduction, and can be broadly classified based on the groups they act on, such as proteins, carbohydrates, and lipids. Protein kinases phosphorylate proteins on serine, threonine, tyrosine, or histidine amino acid residues. Examples include MAP kinases, CDKs, and JAKs. Lipid kinases include phosphatidylinositol kinases like PI3 and PI3K. Carbohydrate kinases such as hexokinase and phosphofructokinase are involved in energy generation pathways. Other notable kinases include pyruvate kinase, which converts phosphoenolpyruvate to pyruvate, and creatine kinase, which is used as an indicator of tissue damage. Visit the supplier page for more product information, including details on enzyme activity.
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- AKT1/PKBα is a serine/threonine kinase that belongs to the AKT family. AKT1 is activated in cells in response to ...
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- Kinase Assay, Western Blot
- AKT2 or Protein Kinase B β (PKBβ) is a serine/threonine kinase that is a member of the AKT family. AKT2 like ...
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- Kinase Assay, Western Blot
- AKT 3 or Protein Kinase B γ (PKBγ) is a serine/threonine kinase that is a member of the AKT family. AKT 3 is...
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- Kinase Assay, Western Blot
- AKT3 or Protein Kinase B γ (PKBγ) is a serine/threonine kinase that is a member of the AKT family. AKT3 is ...
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- Kinase Assay
- ALK or anaplastic lymphoma kinase is a receptor tyrosine kinase that was originally identified as a member of the ...
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- Kinase Assay
- Recombinant Human JAK2 (a.a. 808-end) with N-terminal His-tag was expressed in a baculovirus expression system
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- kinetics, screening inhibitors, and selectivity profiling
- AK5, also known as adenylate kinase isoenzyme 5, is a member of the adenylate kinase family, which is involved in ...
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- SDS-PAGE
- AURORA A belongs to a multigenic family of mitotic serine/threonine kinases which are involved in the control of ...
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- Kinase Assay, Western Blot
- AURORA B is a member of the Aurora kinase family that associates with microtubules during chromosome movement and ...
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- Kinase Assay, Western Blot
- Aurora C is a member of mitotic serine/threonine kinases that regulate centrosome maturation, chromosome segregation, ...
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- Kinase Assay, Western Blot
- The gene encoding BLK is a member of the SRC family of protooncogenes and shows preferential expression in B-lymphoid ...
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- ELISA, Inhibition Assays, Western Blotting
- BLK, also known as B lymphoid kinase, is a 55 kd tyrosine kinases with a SH3, SH2 and catalytic domains that contain ...
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- Kinase Assay, Western Blot
- BLK, also known as B lymphoid kinase, is a 55 kd tyrosine kinases with a SH3, SH2 and catalytic domains that contain ...
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- Kinase Assay, Western Blot
- The BMX gene encodes a non-receptor tyrosine kinase, which may play a role in the growth and differentiation of ...
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- Kinase Assay, Western Blot
- Recombinant Human BTK fused with Proprietary tag at C-terminal was expressed in Insect cells
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- Inhibition Assay
- BUB1B or budding uninhibited by benzimidazoles 1 homolog beta is involved in spindle checkpoint function and has been ...
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- Kinase Assay, Western Blot
- CSK is a cytoplasmic tyrosine kinase that has been shown to downregulate the tyrosine kinase activity of the c-src ...
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- Kinase Assay, Western Blot
- CAMK4 is a multifunctional serine/threonine protein kinase and a member of Ca(2+)/calmodulin-dependent protein kinase ...
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- Kinase Assay, Western Blot
- CAMKK1 or CAMKKα is a Ca(2+)/calmodulin-dependent protein kinase that activatesCaM-kinases I and IV via ...
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- Kinase Assay, Western Blot
- CASK is a calcium/calmodulin-dependent serine protein kinase which is a MAGUK (membrane-associated guanylate kinase) ...
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- Kinase Assay, Western Blot
- CLK/STY is a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. The phosphorylated serine/...
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- Kinase Assay, Western Blot
- CDC-like kinase 2 (CLK2) a family of autophosphorylating kinases termed CLK (CDC2/CDC28-like kinases) was shown to ...
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- Kinase Assay, Western Blot
- CLK3, also known as CDC-like kinase 3, encodes a serine/threonine type protein kinase with a non-conserved N-terminal ...
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- Kinase Assay, Western Blot
- CSK is a cytoplasmic tyrosine kinase that has been shown to downregulate the tyrosine kinase activity of the c-src ...
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- Kinase Assay, Western Blot
- CAMK1 is an enzyme that in humans is encoded bythe CAMK1 gene. CAMK1 is expressed in many tissues and is acomponent of a...
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- ELISA, InhibitionAssays, Western Blot
- Calmodulin (CaM) is an intracellular receptor protein for Ca2+-ions. It activates the myosin light chain kinase which is...
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- ELISA, Inhibition Assays, Western Blotting
- CKMT1A is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It...
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- SDS-PAGE
- Recombinant human CKMT2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using ...
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- SDS-PAGE
- Cyclin-dependent kinase 4, also known as CDK4, belongs to the Cyclin-dependent kinases (CDK) family. CDK are the ...
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- SDS-PAGE
- Death-associated protein kinase 1 (DAPK1) is a positive mediator of apoptosis induced by γ-interferon. Activation ...
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- Kinase Assay, Western Blot
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