Description
STELLARIS DLS (Digital Light Sheet) unites in one place a confocal system and a light sheet microscope – a unique combination aimed to make user research more versatile. The exclusive vertical design of DLS, enabled by Leica Microsystems' proprietary TwinFlect mirrors, allows confocal and light sheet imaging to be combined in the same system, so users can easily adapt their microscopy methods to meet experimental needs. DLS has the capacity to image different types of samples – model organisms, organoids, or cleared tissue. Users benefit from a large excitation spectrum, thanks to the STELLARIS White Light Laser and the ability to perform light sheet imaging while using standard glass bottom plates. Light sheet microscopy usually requires a dedicated optical setup on an independent system, where the illuminating and detecting objectives are perpendicular to each other. DLS makes light sheet microscopy easily accessible. The unique TwinFlect mirror device detects the illuminating light sheet at a 90° angle. This improvement allows the integration of the illumination and detection beam path into the vertical axis of every Leica STELLARIS system with an inverted microscope stand. All this enhancement is achieved without compromising confocal functionality. Superior objectives for a wide range of applications are one of Leica Microsystems’ hallmarks. STELLARIS and DLS synergize to expand the options for user research. For example, users can manipulate specimens using the confocal technology and then image with DLS. It is simply done by switching between confocal and light sheet mode in the LAS X software. This way, photoconversion or wounding experiments with subsequent gentle long-term observations become easy and convenient.