CELENA® X High Content Imaging System from Logos Biosystems

Product Specs
ItemCELENA^® X High Content Imaging System
CompanyLogos Biosystems
Price Get Pricing Get Quote for this Product
Catalog NumberCX30004 / CX30005
Channels4 fluorescence channels and on transmitted light channel
ApplicationsHigh content cell imaging and analysis for fixed and kinetic live assays including (but not limited to) the following applications: 3D Cell Models, Apoptosis, Autophagy, Calcium Signaling, Cell Counting, Cell Cycle, Cell Growth/Proliferation, Cell Migration, Cell Morphology, Cell Viability, Co-localization, Confluency, Cytotoxicity-BF, Cytotoxicity-FL, Histology, Immunofluorescence, NF-KB Translocation, Organoid/Spheroid Morphology, Phagocytosis, Stitching, Transfection Efficiency, Wound Healing
Quantity1 System
Resolution1280 x 1024 pixels
CameraMonochrome: CMOS, 1.92 MP (16 bit or 12-bit dynamic range)
Color: CMOS, 1.92 MP (24 bit)
TypeHigh content image capture, analysis, and quantification system
Light SourceHi-power LED cubes with adjustable intensity (>50,000 hours per filter cube)
Objectives1.25 to 100X objectives
Olympus, Zeiss, or Logos Biosystems objectives
StageMotorized X/Y Stage (120 mm x 80 mm)
Motorized Z Stage (10 mm)
DetectionHigh-power LED filter cubes with adjustable intensity and compatible objectives (filter cubes and objectives are interchangeable)
FormatImages: TIF, PNG, JPG
Movies/Video: MP4
DimensionsCELENA® X Main body: 39 x 46x 50 cm (15.4 x 18.1 x 19.7 in)
CELENA® X Controller: 17 x 30 x 23 cm (6.7 x 11.8 x 9.1 in)
Electrical Requirements100 - 240 VAC, 250 W (120 volts or 2.08 amps), 50/60 Hz
ComponentsBasic package (CX30004) includes: CELENA® X Main Unit, CELENA® X Controller, Phase Contrast Condenser, Monochrome Camera Module, External HP Workstation with 24-inch 4K UHD monitor with CELENA® X Explorer (interface), CELENA® X Cell Analyzer software installed, three (3) filter cubes* (DAPI, eGFP, RFP), three (3) objectives*, and holders* one (1) universal holder and one (1) 2-slide holder. *Additional options available
Advanced package (CX30005) includes everything included in the Basic package plus dual camera module (monochrome and color), laser autofocus module, one (1) additional objective, and (1) additional filter.

Additional Product Information

Supported labware: Slides, Multi-well plates (6 to 1536 wells), Petri dishes, Culture flasks
Filter Cube Stage: Motorized, 4 interchangeable fluorescence filter cubes, 1 brightfield filter cube
Available Filters: DAPI, eGFP, RFP, mCherry, ECFP, EYFP, DSRed, Cy5, Cy7, Cy3/TRITC, Long Pass, GFP Long Pass, Cy5 Long Pass, Custom filters
Objective Turret: Motorized, 5 interchangeable objectives
Available accessories: Joystick controller, Microscope calibration slide

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Logos Biosystems

8F, 18 Gosan-ro 148beon-gil

Gunpo-si, Gyeonggi-do 15850

Korea, Republic of (South Korea)

Phone: +82-31-478-4185
Fax: +82-31-360-4277

Email: sales@logosbio.com

Company Profile

Website: www.logosbio.com

(1) HDAC Inhibition Reshapes Splicing of Synaptic Plasticity-Related Genes and Neural Network DynamicsCellular and Molecular NeurobiologyFebruary 11, 2026A. P. Beletskiy, Yu. A. Leontovich, N. A. Aseyev, P. M. Balaban, A. A. Borodinovaneuron cultures in a 24-well plate were placed in the stage top incubator (Tokai Hit, Japan) in the CELENA X High Content Imaging System (Logos Biosystems, South Korea) (5% CO₂, with a top heater temperature set on 37 °C and a stage heater

(2) Anticancer Effect of Pacificusoside D from the Starfish Solaster pacificus in Combination with 2-Deoxy-D-glucose on Oxidative Phosphorylation in Triple-Negative Breast Cancer Cells MDA-MB-231Marine DrugsFebruary 11, 2026Olesya S. Malyarenko, Timofey V. Malyarenko, Alla A. Kicha, Svetlana P. Ermakova, Natalia V. Ivanchinaincubation, cells were washed with PBS, and 5 mL of DMEM/10 FBS was added. The images were taken under CELENA® X High Content Imaging System (Logos Biosystems, Anyang-si, Gyeonggi-do, South Korea) at 10× objective magnification. The intensity

(3) Heterotypic 3D Model of Breast Cancer Based on Tumor, Stromal and Endothelial Cells: Cytokines Interaction in the Tumor MicroenvironmentCellsJanuary 14, 2026Anastasia Leonteva, Alina Kazakova, Ekaterina Berezutskaya, Anna Ilyina, David Sergeevichev, Sergey Vladimirov, Maria Bogachek, Igor Vakhrushev, Pavel Makarevich, Vladimir Richter, et al.(ImageJ 2.16.0/1/54p, Java 1.8.0_442 (64-bit)). 2.4. Time-Lapse of Spheroid Formation Process The CELENA X High Content Imaging System (Logos Biosystems, Anyang-si, Republic of Korea) was utilized to analyze the process of spheroid formation.

(4) Visualization, Data Extraction, and Multiparametric Analysis of 3D Pancreatic and Colorectal Cancer Cell Lines for High-Throughput ScreeningBiomedicinesJanuary 6, 2026Mikhail A. Trofimov, Ilya P. Bulatov, Velemir S. Lavrinenko, Vladimir E. Popov, Varvara S. Petrova, Anton S. Bukatin, Stanislav F. Tyazhelnikov(PerkinElmer, Waltham, MA, USA) plate reader. On the same day, imaging data were obtained using the Celena X High-Content Imaging system (Logos Biosystems, Gyeonggi-do, Republic of Korea) with Celena X Explorer 1.6.0, followed by morphological

(5) Clinical breakpoint meropenem concentration modulate outer membrane vesicle production in enterotoxigenic Bacteroides fragilisArchives of MicrobiologyJanuary 1, 2026Saniya Kozhakhmetova, Ayazhan Bekbayeva, Elena Zholdybayeva, Tatyana Krivoruchko, Natalya Dashevskaya, Elizaveta Vinogradova, Nazira Kamzayeva, Zhanagul Khassenbekova, Almagul Kushugulova, Samat Kozhakhmetovfor connective tissue differentiation (Gattuso 2009). Microscopic examination was conducted using a CELENA® X High Content Imaging System (Logos Biosystems, South Korea). Three histological sections from each animal were analyzed at all time

(6) Automated smartphone based cell analysis platformNpj ImagingOctober 22, 2025Meryem Beyza Avci, Fatma Kurul, Mehmet Turkan, Arif E. Cetinalgorithms or artificial intelligence (AI)-driven approaches for confluency analysis. For example, the CELENA® X High Content Imaging System (Logos Biosystems) leverages image-processing algorithms to integrate live cell imaging with confluency

(7) The Activity of Human NK Cells Towards 3D Heterotypic Cellular Tumor Model of Breast CancerCellsJuly 8, 2025Anastasia Leonteva, Maria Abdurakhmanova, Maria Bogachek, Tatyana Belovezhets, Anna Yurina, Olga Troitskaya, Sergey Kulemzin, Vladimir Richter, Elena Kuligina, Anna NushtaevaTime-Lapse of Spheroid Formation Process In order to analyze the process of spheroid formation, the CELENA X High Content Imaging System (Logos Biosystems, Anyang-si, Republic of Korea) was used. Cancer and stromal cells were seeded on a

(8) Oncogenic Activity and Sorafenib Sensitivity of ARAF p.S214C Mutation in Lung CancerCancers (Basel)July 4, 2025Carol Lee, Weixue Mu, Xi July Chen, Mandy Sze Man Chan, Zhishan Chen, Sai Fung Yeung, Helen Hoi Yin Chan, Sin Ting Chow, Ben Chi Bun Ko, David Wai Chan, et al.determine the spheroid cells’ viability and apoptotic rate, respectively. Images were taken using the CELENA X High Content Imaging System (Logos Biosystems, Anyang, Republic of Korea). 2.11. RNA Sequencing NCI-H2023 cells expressing EGFP,

(9) Defining core signaling pathways for supporting in vitro maintenance of pig extraembryonic endoderm (XEN) cellsReproductionApril 1, 2025Jinsol Jeong, Dong-Kyung Lee, Kwang-Hwan Choi, Dong-Wook Kim, Seokjong Lee, Jong-Nam Oh, Yelim Ahn, Chang_Kyu Leeslide glass with ProLong Gold with DAPI (Invitrogen). Images of stained cells were captured using a CELENA X high-content imaging system (Logos Biosystems, Korea). Quantitative real-time polymerase chain reaction (qPCR) Total RNA was extracted

(10) Imaging Flow Cytometry in HIV Infection Research: Advantages and OpportunitiesMethods ProtocFebruary 3, 2025Kirill. A. Elfimov, Dmitriy. A. Baboshko, Natalya. M. Gashnikovarespond to different treatments or conditions. For example, researchers used the CELENA X imaging system (CELENA® X High Content Imaging System, Logos Biosystems, ©Aligned Genetics, Inc., Anyang, Gyeonggi-do, Republic of Korea) to study how SARS-CoV-2

(11) RAC1-Amplified and RAC1-A159V Hotspot-Mutated Head and Neck Cancer Sensitive to the Rac Inhibitor EHop-016 In Vivo: A Proof-of-Concept StudyCancers (Basel)January 23, 2025Helen Hoi Yin Chan, Hoi-Lam Ngan, Yuen-Keng Ng, Chun-Ho Law, Peony Hiu Yan Poon, Ray Wai Wa Chan, Kwok-Fai Lau, Wenying Piao, Hui Li, Lan Wang, et al.ultra-low-attachment plates for spheroid formation (cat. #3473, Corning, USA). Growth of spheroids was monitored by CELENA X High Content Imaging System (Logos Biosystems, Annandale, VA, USA). Bright-field images (10× magnification) were taken 96 h after

(12) Thermally Triggered Double Emulsion‐Integrated Hydrogel Microparticles for Multiplexed Molecular DiagnosticsAdvanced ScienceJanuary 16, 2025Eui Ju Jeon, Seungwon Jung, Yoon‐ha Jang, Seoyoung Lee, Song‐Ee Choi, So Young Jeon, Lankyeong Yoon, Bong Kyun Kim, Tae Jong Kim, Kuenyoul Park, et al.TaqPIN The dimension and fluorescence intensity of TaqPIN were measured using fluorescence microscopy (Celena X High Content Imaging System, Logos Biosystems, Korea). To evaluate encapsulation efficiency, TaqPINs were fabricated with DEs containing

(13) Kombucha Versus Vegetal Cellulose for Affordable Mucoadhesive (nano)FormulationsGelsJanuary 4, 2025Ioana Popa-Tudor, Naomi Tritean, Ștefan-Ovidiu Dima, Bogdan Trică, Marius Ghiurea, Anisoara Cimpean, Florin Oancea, Diana Constantinescu-AruxandeiGermany). After performing the LIVE/DEAD assay, HGF-1 cells were visualized using a cell imaging system (Celena® X High Content Imaging System (Logos Biosystems, Gyeonggi-do, South Korea)). The image acquisition was performed using Celena® X Explorer

(14) Single-cell RNA-sequencing of BK polyomavirus replication in primary human renal proximal tubular epithelial cells identifies specific transcriptome signatures and a novel mitochondrial stress patternJournal of VirologyDecember 17, 2024Fabian H. Weissbach, Océane M. Follonier, Svenia Schmid, Karoline Leuzinger, Michael Schmid, Hans H. Hirschwith ProLong gold antifade mountant (P36941, Thermo Fisher Scientific). Images were acquired with a Celena X High Content Imaging System (Logos Biosystems). For quantification, images of five randomly selected fields of view per sample were

(15) Specific Activation of the Expression of Growth Factor Genes in Expi293F Human Cells Using CRISPR/Cas9-SAM Technology Increases Their ProliferationActa NaturaeNovember 12, 2024P. A. Bobrovsky, E. N. Grafskaia, D. D. Kharlampieva, V. A. Manuvera, V. N. Lazarevcontaining 10% FBS in a carbon dioxide incubator at 37°C and 5% CO2 for 24 h, then transferred to a Celena X High Content Imaging System (Logos Biosystems, Republic of Korea) for live cell imaging, and cultured in an isolated chamber at

(16) Subinhibitory concentrations of meropenem stimulate membrane vesicle production and modulate immune response in Bacteroides fragilis infectionCurrent Research in Microbial SciencesNovember 11, 2024Saniya Kozhakhmetova, Ayazhan Bekbayeva, Elena Zholdybayeva, Tatyana Krivoruchko, Natalya Dashevskaya, Zhanel Mukhanbetzhanova, Elizaveta Vinogradova, Almagul Kushugulova, Samat Kozhakhmetovconnective tissue differentiation (Gattuso et al., 2009). Microscopic examination was performed using a CELENA® X High Content Imaging System (Logos Biosystems). Three histological sections were analyzed from each animal at all time points. Each

(17) Mechanistic insights into the plant biostimulant activity of a novel formulation based on rice husk nanobiosilica embedded in a seed coating alginate filmFrontiers in Plant ScienceMay 21, 2024Naomi Tritean, Bogdan Trică, Ştefan-Ovidiu Dima, Luiza Capră, Raluca-Augusta Gabor, Anisoara Cimpean, Florin Oancea, Diana Constantinescu-AruxandeiAfterward, the leaves were washed with double-distilled water. Intracellular ROS were visualized using CELENA® X High Content Imaging System (Logos Biosystems, Annandale, VA, USA). Mean fluorescence intensity was measured in the ImageJ software

(18) N-glycomic profiling of capsid proteins from Adeno-Associated Virus serotypesGlycobiologyMarch 19, 2024Yongjing Xie, Michael ButlerEm530/50) against total cells stained with Hoechst 33,342 (DAPI filter cube: Ex375/28, Em460/50) on a CELENA ® X high content Imaging System (Logos Biosystems, Villeneuve d’Ascq, France). About 30.0 mL of each transfection was centrifuged at

(19) Shear stress induces autophagy in Schlemm’s canal cells via primary cilia-mediated SMAD2/3 signaling pathwayAutophagy ReportsDecember 31, 2023Myoung Sup Shim, Angela Dixon, April Nettesheim, Kristin M. Perkumas, W. Daniel Stamer, Yang Sun, Paloma B. Litonfrom Santa Cruz Biotechnology. Live cell time lapse imaging Live cell images were captured using the CELENA® X High Content Imaging System (Logos biosystems, Annandale, VA, USA), equipped with high power LED filters coupled with the ibidi

(20) Novel Anti-Mesothelin Nanobodies and Recombinant Immunotoxins with Pseudomonas Exotoxin Catalytic Domain for Cancer TherapeuticsMol CellsDecember 31, 2023Minh Quan Nguyen, Do Hyung Kim, Hye Ji Shim, Huynh Kim Khanh Ta, Thi Luong Vu, Thi Kieu Oanh Nguyen, Jung Chae Lim, Han Choesyringe filters were from Pall South Korea (Korea). The SRT-C SEC 300 column was from Sepax (USA). The CELENA X High Content Imaging System was from Logos Biosystems (Korea). Screening of the nanobody library The nanobody library screening

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CELENA^® X High Content Imaging System

CELENA^® X High Content Imaging System from Logos Biosystems

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Logos Biosystems

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CELENA^® X High Content Imaging System from Logos Biosystems

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