8-hydroxy 2 deoxyguanosine ELISA Kit ab201734 from Abcam

Product Specs
Item8-hydroxy 2 deoxyguanosine ELISA Kit
CompanyAbcam
Price $639.00Supplier Page View Company Product Page
Catalog Numberab201734
Detection Range0.94 - 60 ng/ml
SensitivityEqual to 0.59 ng/mL
ApplicationscELISA, ELISA
Quantity1 x 96 Tests

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

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(1) Cockayne syndrome mutation in XPG activate the integrated stress responseHuman GeneticsDecember 1, 2026Danhui Zhang, Max Hartmann, Zhouli Cao, Gaojie Zhu, Gregoire Najjar, Cagatay Günes, Steffen Emmert, Karin Scharffetter-Kochanek, Sebastian IbenELISA 8-OHdG levels in all cell lines were measured by using the 8-hydroxy-2-deoxyguanosine ELISA Kit (ab201734, Abcam). gDNA extraction was performed as previously described. 30μg gDNA was digested by using 600

(2) Interplay of Vitamin D3, Wnt/β-Catenin Pathway, and Oxidative DNA Injury in CMS-Induced Depression ModelBiomedicinesApril 24, 2026May M. Alrashed, Hajera Tabassum, Dara Aldisi, Maha H. Alhussain, Sadia Arjumand, Mahmoud M. A. Abulmeatypreviously described [23]. The level of oxidative DNA damage was quantified using the 8-OHdG ELISA Kit (ab201734, Abcam, UK) according to the manufacturer’s protocol. Absorbance was recorded at 450 nm using a microplate

(3) Microbe-associated molecular patterns differentially mediate carcinogenic alterations of the breast tissue in the context of obesityNeoplasiaMarch 1, 2026Mohamed Gaber, Lauren M. Moulden, Adam S. Wilson, Valerie Payne, Julia Holmes, Kayla Neary, Abigail Peoples, Mary L. Duet, Adam J. Katz, Pierre-Alexandre Vidi, et al.liberate the individual bases. 8-OHdG was measured in undiluted DNA extracts by competitive ELISA (Abcam; ab201734), according to the manufacturer’s protocol. Comet assay To assess DNA damage in breast acini cultures,

(4) Beyond readthrough: ataluren restores mitochondrial function and reduces oxidative stress in FANCA-mutated cells via mTOR–DRP1 modulationCell Death DiscoveryFebruary 28, 2026Matilde Balbi, Elisa Guidi, Anca Manuela Hristodor, Fabio Corsolini, Vanessa Cossu, Roberta Bottega, Martina Serra, Sara Pestarino, Martina Bartolucci, Marco Cipolli, et al.[53]. Oxidative DNA damage was evaluated by measuring 8-OHdG levels using a commercially available ELISA kit (#ab201734, Abcam, Cambridge, UK), following the manufacturer’s protocol. Western blot analysis Western blot (WB

(5) MEGF9 prevents lipopolysaccharide-induced cardiac dysfunction through activating AMPK pathwayRedox ReportDecember 31, 2025Zhili Jin, Xianqing Li, Huixia Liu, Tao He, Wanli Jiang, Li Peng, Xiaoyan Wu, Ming Chen, Yongzhen Fan, Zhibing Lu, et al.(#ab118970), 3-Nitrotyrosine ELISA Kit (#ab116691), 8-hydroxy 2 deoxyguanosine (8-OHdG) ELISA Kit (#ab201734), Mouse IL-6 ELISA Kit (#ab222503), Rat IL-6 ELISA Kit (#ab234570), Mouse TNF-α ELISA Kit (#ab208348)

(6) Fine Particulate Matter (PM) Effects on Swine Granulosa and Ovarian Endothelial CellsAnimals (Basel)December 27, 2025Giuseppina Basini, Roberto Ramoni, Stefano Grolli, Simona Bussolati, Laura Assogna, Francesca Grasselliconcentrations. To quantify 8-OHdG levels, a competitive ELISA assay was performed using the 8-OHdG ELISA Kit (ab201734; Abcam, Cambridge, UK). This kit detects both free 8-OHdG and DNA-incorporated 8-OHdG. The ELISA assay

(7) Darbepoetin plus slow-release IntraVenous Iron to decrease transfusions and improve iron status and neurodevelopment in preterm infants (DIVI): study protocol for a randomized, blinded phase II trialTrialsDecember 22, 2025Sandra E. Juul, Bryan A. Comstock, Dennis E. Mayock, Kendell German, John Feltner, Jill Irvine, Eliza Lagerquist, Patrick J. Heagerty8-hydroxy-2-deoxyguanosine (8-OHdG) will be assayed in urine before and 1 week after iron administration (Abcam ELISA ab201734). We will measure urine superoxide dismutase at the same time points as MDA and 8-OHdG (Abcam, ab119520).

(8) Cannabidiol Mitigates Pollution-Induced Inflammatory, Oxidative, and Barrier Damage in Ex Vivo Human SkinBiomoleculesDecember 20, 2025Klinngam W, Loruthai O, Vimolmangkang S.Cambridge, MA, USA). Oxidative DNA damage marker 8-OHdG and PIP were measured by ELISA using kits #ab201734 and #ab272198 (Abcam, USA), respectively. Fluorescence and absorbance signals were recorded on a SpectraMax

(9) The Potential of Ectoine as a Brain Anti-Aging Agent in Rat Model of D-Galactose-Accelerated Aging May Be Mediated Through Crosstalk Between Redox/Mitochondrial Homeostasis/Autophagic/Apoptotic PathwaysMol NeurobiolDecember 8, 2025Aisha H. A. Alsenousy, Marwa B. Bakir, Mohammed S. Zommara, Hanan A. Edres, Wael S. Darwish, Rania M. H. M. Eid, Maher A. Kamelwas then used to determine 8-OHdG concentrations using a commercially available 8-OH-dG ELISA kit (ab201734, Abcam, Cambridge, UK), strictly adhering to the manufacturer’s instructions. Determination of Malondialdehyde

(10) NFS1, together with FXN, protects cells from ferroptosis and DNA damage in diffuse large B-cell lymphomaRedox BiologyNovember 1, 2025Xue Shi, Yun Zhao, Hong-Yu Gao, Wei Yang, Jun Liao, Hui-Han Wang, Xiao-Tian Wang, Wei Yanlesions were quantified using a commercial 8-hydroxy-2′-deoxyguanosine (8-oxo-dG) ELISA kit (Abcam, Cat# ab201734) according to the manufacturer's protocol. Genomic DNA was isolated from DLBCL cells using a DNA extraction

(11) Cardiovascular comorbidities are risk factors for increased oxidative stress and DNA damage in migraine patients: a prospective cohort studyJ Transl MedOctober 8, 2025Mustafa Gokce, Muhammed Yunus Bektay, Mustafa Uzun, Can Ulutas, Ferda Uslu, Eray Metin Gulercomet assay, which is a method based on alkaline single-cell gel electrophoresis [27] (Abcam, UK; Cat. No: ab201734). To achieve this goal, 6 µL of whole blood was combined with 0.7% low melting point agarose and spread

(12) Multivalent binding of the tardigrade Dsup protein to chromatin promotes yeast survival and longevity upon exposure to oxidative damageNature communicationsSeptember 29, 2025Aguilar RR, Khan LF, Cummins CK, Arslanovic N, Grauer T, Birmingham K, Kasliwal K, Posnikoff SDL, Chakraborty U, Hickman AR, et al.normalized. ELISA to measure 8-hydroxy 2-deoxyguanosine (8-OhdG) was performed as per kit instructions (Abcam ab201734). For each sample 15 μg DNA was assayed in triplicate (three independent cultures for each condition)

(13) Alpha-Lipoic Acid and Metformin Combination Therapy Synergistically Activate Nrf2-AMPK Signaling Pathways to Ameliorate Cognitive Dysfunction in Type 2 Diabetic Encephalopathy: A Preclinical StudyBiology (Basel)July 18, 2025Abdulmajeed F. Alrefaei, Mohamed E. Elbeehsubstances methodology [57]. DNA oxidative damage assessment employed 8-OHdG competitive ELISA (catalog #ab201734, Abcam, Cambridge, UK). Protein carbonyl determination used dinitrophenylhydrazine methodology [58]. Antioxidant

(14) Salvianolic Acid B Alleviates LPS-Induced Spleen Injury by Remodeling Redox Status and Suppressing NLRP3 InflammasomeAntioxidants (Basel)July 18, 2025Hao Wang, Xiao Dou, Ruixue Wang, Yuxin Jiang, Jinsong Zhang, Xianjuan Qiao, Yingjun Liu, Hao Zhang, Chenhuan Lai, Yanan Chen, et al.(Nanjing Jiancheng Bioengineering Institute, Nanjing, China). 8-Hydroxy-2′-deoxyguanosine (8-OHdG, ab201734) level in the homogenate was measured with an ELISA kit (Abcam, Cambridge, MA, USA). 2.9. Measurement

(15) Inhibition of AMPKα Pathway by Podocyte GOLM1 Exacerbates Diabetic Nephrology in MiceAdvanced ScienceJuly 13, 2025Peng Xu, Kaiqiang Li, Huasong Liu, Aibo Xu, Zhewei Zhang, Yimin Yang, Xiaobo Lai, Ke Hao, Kui Fang, Zeyu Lai, et al.3‐Nitrotyrosine (3‐NT), and 8‐hydroxy 2 deoxyguanosine (8‐OHdG), commercial kits (#ab118970, #ab116691, #ab201734, Abcam, Cambridge, UK) were used. To measure NF‐κB activity, nuclear extracts were prepared and mixed

(16) miR-29a-3p and TGF-β Axis in Fanconi anemia: mechanisms driving metabolic dysfunction and genome stabilityCell Mol Life SciJune 25, 2025Nadia Bertola, Stefano Regis, Vanessa Cossu, Matilde Balbi, Martina Serra, Fabio Corsolini, Cristina Bottino, Paolo Degan, Carlo Dufour, Filomena Pierri, et al.[21]. To measure 8-hydroxy-2-deoxyguanosine (8-OHdG), a biomarker of oxidative DNA damage, an ELISA kit (#ab201734, Abcam, Cambridge, UK) was utilized according to the manufacturer’s instructions. Evaluation of aerobic

(17) Toxicological impact of Thiamethoxam on adult male rats: Histopathological, biochemical, and oxidative DNA damage assessmentToxicology ReportsJune 1, 2025Sahar Y. Issa, S.M. Abdel Rahman, Yasmin M. Gaber, Nada A.H. Solimanmethod. The quantification of 8-OH-2DG levels was performed using an ELISA-based kit (Catalogue No. ab201734, Supplier: Abcam). This kit has a detection sensitivity of 0.1 ng/mL and high specificity and sensitivity

(18) N-acetyl-L-cysteine improves mitochondrial and oxidative defects in the acadian variant of fanconi syndromeExp Biol Med (Maywood)May 23, 2025Inas Al-Younis, Rebeca Martín-Jiménez, Mehtab Khan, Yann Baussan, Caroline Jose, Yves Thibeault, Etienne Hebert-Chatelainmanufacturer’s instructions. DNA oxidative damage were determined by measuring the 8-OHdG levels by ELISA (ref. ab201734, Abcam) following manufacturer’s instructions. Complex I activity For complex I activity, fibroblasts

(19) Oxidative Stress Modulation and Glutathione System Response During a 10-Day Multi-Stressor Field TrainingJ Funct Morphol KinesiolMay 10, 2025Liāna Pļaviņa, Edgars EdelmersPeroxidation (MDA) Assay Kit (Cat.# MAK085; Sigma-Aldrich, USA);8-Hydroxy-2′-deoxyguanosine ELISA Kit (Cat.# ab201734; Abcam, Cambridge, UK). Calculation of oxidative-stress index (OSI): Consistent with Erel [21,22], OSI

(20) Efficacy and Safety of Visible and Near-Infrared Photobiomodulation Therapy on Astenospermic Human Sperm: Wavelength-Dependent Regulation of Nitric Oxide Levels and Mitochondrial EnergeticsBiology (Basel)May 1, 2025Matilde Balbi, Rachele Lai, Sara Stigliani, Claudia Massarotti, Matteo Bozzo, Paola Scaruffi, Silvia Ravera, Andrea Amaroli8-hydroxy-2′-deoxyguanosine (8-OHdG) was assessed using the high-sensitivity ELISA assay (Kit-code: ab201734 from Abcam plc, Discovery Drive, Cambridge Biomedical Campus, Cambridge, UK) [64]. 2.6. Detection of

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8-hydroxy 2 deoxyguanosine ELISA Kit from Abcam

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8-hydroxy 2 deoxyguanosine ELISA Kit from Abcam

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