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PRKG1 (PKG) Kinase Enzyme System
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PRKG1 (PKG) Kinase Enzyme System
PRKG1 (PKG) Kinase Enzyme System
PRKG1 (PKG) Kinase Enzyme System from Promega
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(1)
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PRKG1 (PKG) Kinase Enzyme System
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Description
Recombinant full-length human PRKG1 (PKG) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. PRKG1 is a homodimer, with each monomer containing a regulatory cGMP-binding domain and a catalytic domain
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Product Specs
Item
PRKG1 (PKG) Kinase Enzyme System
Company
Promega
Price
Supplier Page
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Catalog Number
V4248
Quantity
10microg
Molecular Weight
~100kDa
Components
Kinase:
PRKG1, 10µg (Human, recombinant full-length)
Other:
cGMP Solution, Reaction Buffer A, DTT
Substrate:
RSK Substrate (KRRRLSSLRA); derived from human 40S ribosomal protein S6 (amino acids 230–239)
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Promega
2800 Woods Hollow Rd
Madison
,
WI
53711
United States
Phone
: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516
Email: custserv@promega.com
techserv@promega.com
Company Profile
Website:
http://www.promega.com
Citations (1)
(1)
Sensing Cytosolic DNA Lowers Blood Pressure by Direct cGAMP-Dependent PKGI Activation
Circulation
September 26, 2023
Su J, Coleman P, Ntorla A, Anderson R, Shattock MJ, Burgoyne JR.
PKG by cGAMP or cGMP was assessed using the PRKG1 (PKGI) Kinase Enzyme System (
Promega
, catalog no.
V4248
) and
ADP-Glo Kinase Assay
(
Promega
, catalog no.
V9101
). In brief, the PRKG1 was prepared according to
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PRKG1 (PKG) Kinase Enzyme System from Promega
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