Description
Fibronectins interact with cell surfaces and various compounds, including collagen, fibrin, heparin, DNA, and actin. They play roles in cell adhesion, cell motility, opsonization, wound healing, and maintaining cell shape. In rabbits, the FN1 gene encodes fibronectin. It is crucial for osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, which is essential for osteoblast mineralization. Additionally, fibronectin aids in regulating type I collagen deposition by osteoblasts. In a rabbit corneal alkali burn model, FN significantly improved corneal healing by reducing epithelial cell exfoliation and promoting re-epithelialization