Description
dsDNA (double-stranded DNA) is the main carrier of genetic information, and its functions include storing genetic information, regulating gene expression, and participating in basic biological processes such as cell division. Systemic lupus erythematosus (SLE) is a severe condition characterized by immune system dysregulation, leading to excessive production of pathogenic autoantibodies and their increased presence in the serum, along with various immune-system-mediated injuries. SLE is marked by high levels of serological autoantibodies, including those targeting double-stranded DNA (dsDNA). dsDNA can bind to proteins to form specific complexes. Regulation of gene expression in rabbits may involve dsDNA breakage and repair processes similar to other mammals