Description
Endothelial cell-specific molecule 1 is a secreted protein primarily expressed in endothelial cells. Its expression is regulated by cytokines, indicating a potential role in endothelium-dependent pathological disorders. In rabbits, this protein is encoded by the ESM1 gene. The functions of ESM1 in rabbits may include regulation of angiogenesis, participation in the regulation of the tumor microenvironment, and as a potential therapeutic target. The specific mechanisms of these functions need to be verified by further studies, but the available information suggests that ESM1 has an important role in vascular biology and disease processes