Description
Aconitate hydratase, also known as aconitase, is an enzyme that plays a crucial role in the tricarboxylic acid (TCA) cycle, also known as the citric acid cycle or Krebs cycle. Aconitate Hydratase, Mitochondrial is encoded by the ACO2 gene in pigs. ACO2 is known to be inactivated by 4-hydroxy-2-(E)-nonenal (HNE), and elevated concentrations of HNE-adducted ACO2 have been associated with disease states