Description
Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide that primarily regulates the growth, maintenance, proliferation, and survival of specific target neurons. As an endogenously produced peptide growth factor, NGF plays a vital role in the natural corneal wound healing process. In a rabbit model, treatments with NGF and KGF-2 proved effective for promoting early re-epithelialization and reducing inflammation, opacity, and neovascularization following a corneal alkali burn. In studies in rabbits, NGF has also been found to have an effect on key sperm characteristics