Description
The MMP9 gene encodes Matrix Metalloproteinase 9 in rabbits. This enzyme is a matrix metalloproteinase that is crucial for the local breakdown of the extracellular matrix and facilitates leukocyte migration. It may also contribute to bone osteoclastic resorption. MMP9 expression in rabbit liver tissues is associated with the activation of multiple signaling pathways (e.g., PI3K, ERK1/2, and JNK), which may be involved in the regulation of inflammatory and immune responses. MMP9 expression is strongly associated with angiogenesis in a rabbit atherosclerotic plaque model