Description
C5b-9 plays a crucial role in inflammation by promoting cell proliferation and rescuing apoptotic cells. The assembly of C5b-9 on cell membranes leads to the formation of transmembrane channels, ultimately resulting in cell death. However, when the number of C5b-9 molecules is limited, nucleated cells can evade cell death through endocytosis and shedding of membranes containing C5b-9. The function of sC5b-9 (soluble membrane attack complex) in rabbits is primarily related to its role in the complement system. Studies have shown that an effective mechanism for the clearance of sC5b-9 exists in rabbits. The half-life of sC5b-9 in plasma of healthy rabbits is approximately 30-50 minutes