Fig 1: Delta change in resting monocyte HSP72 MFI relative to the resting value obtained on day 1 of acclimation (A); and delta change in pre to post-exercise mHSP72 MFI relative to daily resting mHSP72 MFI (B). Box plots show all individual data points (dots), the 25 and 75th interquartile ranges (boxes), and the median (mid-line). Whiskers illustrate the highest and lowest value. Letters illustrate changes from the resting mHSP72 value obtained on day 1 of acclimation between experimental groups. a, b, c illustrates p < 0.01, < 0.001, and < 0.0001 compared to control respectively; d and e illustrate p < 0.01 and < 0.001 compared to hypoxia respectively. Within group changes in mHSP72 relative to the resting mHSP72 value obtained on day one of acclimation (A) or pre to post-exercise (B) are illustrated by *p < 0.05 and #p < 0.01).
Fig 2: Extracellular HSP72 before and after exercise on day 1 and day 10 of the acclimation intervention for all individual participants (A); and percent change in eHSP72 from pre to post-exercise on day 1 and day 10 of acclimation (B). Box plots show all individual data points (dots), the 25 and 75th interquartile ranges (boxes), and the median (mid-line). Whiskers illustrate the highest and lowest value. For display purposes one participant with high eHSP72 values is not included in panel A (day 1 pre, 17.8 ng.mL−1, day 1 post, 24.4 ng.mL−1; Day 10 pre, 15.6 ng.mL−1, Day 10 post, 19.1 ng.mL−1). P-values indicate differences relative to pre-trial resting values within each experimental group (B).
Fig 3: Diagnosis of sludge is marked by lower HSP70 levels, which are inversely associated with cervix size, SOD activity, and lipoperoxidation. A, Heatmap showing correlations between parameters. B, HSP70 levels among pregnant women with or without sludge (Mann–Whitney). C, Cervix length compared among pregnant women with and without sludge according to the HSP70 levels (2‐way ANOVA: HSP70: F1,56 = 5.572; p = .021. Sludge: F1,56 = 6.167; p = .016. Interaction between factors: F1,56 = 1.942; p = .169). D, Pearson's correlation between HSP70 levels and cervix size. E, Association between HSP70 levels and SOD activity. F, Pearson's correlation between HSP70 levels and lipoperoxidation.
Supplier Page from Enzo Life Sciences, Inc. for AMP'D® HSP70 high sensitivity ELISA kit