Fig 1: miR-21-5p is upregulated in patients with myocardial I/R damage history and is positively correlated with myocardial injury markers. (A) RT-qPCR detection of miR-21-5p expression. (B) Pearson correlation analysis of miR-21-5p with IMA and H-FABP. Ⅰ, myocardial ischemia + sevoflurane group (n = 30); II, myocardial ischemia + propofol group (n = 31); III, normal + sevoflurane group (n = 28). Data were analyzed using one-way ANOVA and Pearson correlation analysis. Ⅰ vs. II, Ⅰ vs. III. ****P < 0.0001.
Fig 2: Sevoflurane alleviates myocardial I/R damage and reduces postoperative complications. (A) ELISA kits for IMA and H-FABP expression. (B) ELISA kits for IL-1β, TNF-α, and IL-6 expression. I, myocardial ischemia + sevoflurane group (n = 30); II, myocardial ischemia + propofol group (n = 31); III, normal + sevoflurane group (n = 28). Data were analyzed using one-way ANOVA. I vs. II, I vs. III. ****P < 0.0001.
Supplier Page from Abcam for Rat H-FABP ELISA Kit