Description
Romiplostim (Nplate®) is a thrombopoietin receptor agonist widely used for the treatment of immune thrombocytopenia (ITP) by stimulating platelet production. Due to substantial inter-individual pharmacokinetic variability and the clinical need to optimize dosing, accurate measurement of circulating romiplostim levels is important for PK studies, exposure–response evaluation and supporting individualized therapy.Using Romiplostim -specific antibodies as both coating and capture reagents, we have developed a highly sensitive ELISA kit for quantifying Romiplostim