Description
A general selective indicator for the detection of highly Reactive Oxygen Species (hROS), such as Hydroxyl Radical (-OH), Peroxynitrite(ONOO-), and hypochlorite (-OCl). It has little reactivity with other ROS.
Aminophenyl fluorescein (APF), developed by Tetsuo Nagano, is a general selective indicator for the detection of highly Reactive Oxygen Species (hROS). The probe has little reactivity towards other ROS such as: singlet oxygen (O21), superoxide (O2– -), hydrogen peroxide (H2O2), nitric oxide (NO-), and alkyl peroxide (RO2-). APF is a cell permeable indicator that can be used to detect Hydroxyl Radical (-OH), Peroxynitrite (ONOO-) and hypochlorite (-OCl) production in cells