Description
Cayman’s LipidLaunch™ Loadable LNP SM-102 Kit provides cargo-ready, empty, lyophilized SM-102 LNPs specially formulated for in vitro RNA transfection. Following resuspension, these LNPs are capable of rapid encapsulation of RNA, without the need for incubation steps, enabling subsequent delivery to target cells. LipidLaunch™ Loadable LNPs demonstrate very low toxicity compared to traditional lipid-based transfection methods. Conventionally loaded LNPs typically require specialized equipment to ensure consistent control of particle size, while also requiring larger reaction volumes. LipidLaunch™ Loadable SM-102 LNPs enable users to encapsulate RNA cargo in reaction volumes as low as 50 µl, offering greater flexibility in the scale of preparation while preserving costly RNA cargo.LipidLaunch™ SM-102 LNP (Loadable) performance is dependent on a variety of factors, including cargo type and cell line, so optimization of these parameters is necessary. To aid in optimization, consider using Cayman’s LipidLaunch™ LNP Screening Set (Loadable) (Item No. 502868) or LipidLaunch™ SM-102 LNPs preloaded with luciferase, mCherry, or GFP mRNA (Item Nos. 39318 : 39319 : 39320)