Description
IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoiesis, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines.
Murine IL-3 Pre-Coated ELISA (Enzyme-Linked Immunosorbent Assay) kit is a solid phase immunoassay specially designed to measure IL-3 with a 96-well strip plate that is pre-coated with mouse monoclonal antibody specific for IL-3. It contains E Coli-expressed recombinant IL-3. The detection antibody is a biotinylated goat polyclonal antibody specific for IL-3. The kit is analytically validated with ready to use reagents