Description
beta-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. beta-NGF is a potent neurotrophic factor that signals through its receptor beta-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. beta-NGF also acts as a growth and differentiation factor for B lymphocytes, and enhances B-cell survival.
Murine beta-NGF Pre-Coated ELISA (Enzyme-Linked Immunosorbent Assay) kit is a solid phase immunoassay specially designed to measure beta-NGF with a 96-well strip plate that is pre-coated with mouse monoclonal antibody specific for beta-NGF. It contains NS0-expressed recombinant beta-NGF. The detection antibody is a biotinylated goat polyclonal antibody specific for beta-NGF. The kit is analytically validated with ready to use reagents