Description
Enzyme Immunoassay for the estimation of Fibrinogen (Fbg) in serum and plasma, tissue homogenates and other biological fluids. Fibrinogen is a 340kDa hexameric plasma glycoprotein synthesized by the liver and is the major structural component of a clot, that circulates in the blood of all vertebrates. During tissue and vascular injury, it is converted enzymatically by thrombin to fibrin and then to a fibrin-based blood clot. Fibrin clots function primarily to occlude blood vessels to stop bleeding.Several disorders in the quantity and/or quality of fibrinogen cause pathological bleeding, pathological blood clotting, and/or the deposition of fibrinogen in the liver, kidneys, and other tissues.The normal concentration of fibrinogen in blood plasma is 150400 mg/dl, with levels appreciably below or above this range associated with pathological bleeding and/or thrombosis. Fibrinogen has a circulating half-life of ~4 days ELISA Features include: – Ready to use protocol – Standardisation and High Reproducibility – Lot to Lot Consistency – Accuracy and Precision Validated against seven points for a Gold Ring Standard Quality ELISA – the benchmark sign for Krishgen quality. The GENLISA ELISA kits are used for assessing the specific biomarker in samples analytes which may be serum, plasma, biological fluids and cell culture supernatant