Description
Understanding hepatotoxicity of new drug candidates is one of the major challenges in drug discovery. Hepatocytes derived from human IPS Cells offer a virtually unlimited source of cells, are easy to culture, and provide reliable and reproducible starting material for specific testing. QualiStem® IPS Cell Hepatocyte Differentiation Kit contains optimized components ensure highly enriched populations of hepatocyte-like cells. Cells differentiated using QualiStem® IPS Cell Hepatocyte Differentiation Kit express high levels of hepatocyte markers, including Asialogycoprotein Receptor 1, alpha-Fetoprotein, Hepatocyte Nuclear Factor 4 alpha, CEBP-alpha, Cytokeratin 18 and Serpin A1. This kit maximizes workflow efficiency and is applicable for drug toxicity and small molecule screening. This kit has been tested on multiple induced pluripotent stem cell lines