Description
SARS-CoV-2 Surrogate Virus Neutralization Test Kit( L452R, T478K)is a blocking ELISA detection tool, which mimics the virus neutralization process. The kit contains two key components: the HRP labeled recombinant human ACE2 and the SARS-CoV-2 RBD( L452R, T478K)protein. The protein-protein interaction between RBD( L452R, T478K)and ACE2-HRP can be blocked by neutralizing antibodies against SARS-CoV-2 RBD(E484K,K417T,N501Y).
SARS-CoV-2 Surrogate Virus Neutralization Test Kit( L452R, T478K)can detect circulating neutralizing antibodies against SARS-CoV-2 that block the interaction between the receptor binding domain of the viral spike glycoprotein RBD( L452R, T478K)with the ACE2 cell surface receptor. The assay detects any antibodies in serum and plasma that neutralize the RBD(E484K,K417T,N501Y)-ACE2 interaction. The test is both species and isotype independent