Bio-Plex Multiplex SARS-CoV-2 Serology Assay Kits and Reagents from Bio-Rad

Description

The Bio-Plex SARS-CoV-2 Serology Assays* provide COVID-19 researchers with sensitive and specific assays to monitor the antibody immune response profile against four viral proteins. They are Luminex bead-based multiplex immunoassays that provide sensitive and specific measurements of antibodies against four SARS-CoV-2 proteins: nucleocapsid, receptor binding domain, spike 1, and spike 2 viral proteins. The isotype-specific antibodies detected are IgA, IgG, and IgM, providing the spectrum of humoral response over time after COVID-19 vaccine administration or natural exposure to SARS-CoV-2.

Individual assay components are also available, offering the flexibility to assay only the antibodies of interest. The viral-protein-coated beads can be used to assay antibodies in multiple species and only need to be paired with a species-specific biotinylated antibody for detection. Bio-Plex Pro reagent kits can be used to further streamline assay configuration.

* Bio-Plex Pro SARS-CoV-2 Serology Assays are for research use only.

Product Specs
ItemBio-Plex Multiplex SARS-CoV-2 Serology Assay Kits and Reagents
CompanyBio-Rad
Price Supplier Page View Company Product Page
Catalog NumberBio-Plex Multiplex SARS-CoV-2
MethodImmunoassay
Regulatory StatusRUO
Detection TargetDetects antibodies against four SARS-CoV-2 proteins: nucleocapsid, receptor binding domain, spike 1, and spike 2 viral proteins. Three isotype-specific antibodies are detected: IgA, IgG, and IgM.
ApplicationsDetect antibody response to specific viral subunits to understand each protein's immunogenicity profile, Monitor dosing levels and efficacy in preclinical and clinical trials, Determine effectiveness of vaccine over time through seropositive results during post-market surveillance
Brand/TrademarkBio-Plex

Additional Product Information

Human samples require four components for a complete assay: Antigen-coupled beads, Isotype-specific detection antibody, Isotype-specific control set, Human Serology Assay Reagent Kit (12014777)

For samples from other species, researchers must provide their own biotinylated anti-species detection antibody, positive and negative controls, and select a reagent kit appropriate for the chosen species: Bio-Plex Pro Reagent Kit V (12002798) — for mouse and rat, Bio-Plex Pro Reagent Kit III (171304090M) — for other species