Description
Product Characteristics: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of C1q in human serum, plasma, tissue homogenates, cell lysates, cell culture supernates.
Target Information: C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes