Description
Product Characteristics: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of ISR in rat serum, plasma, tissue homogenates, cell lysates, cell culture supernates.
Target Information: After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]