Description
Product Characteristics: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of S100A4 in serum, plasma, tissue homogenates, cell lysates, cell culture supernates. Due to the high homology of the sequence among different species, the kit can be used to detect human, mouse and rat samples.
Target Information: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]