Description
Product Characteristics: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of SRD5a2 in mouse serum, plasma, tissue homogenates, cell lysates.
Target Information: This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH). [provided by RefSeq, Jul 2008]