Rat IL-18 DuoSet ELISA DY521-05 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRat IL-18 DuoSet ELISA
CompanyR&D Systems, a Bio-Techne Brand
Price $450.00Supplier Page View Company Product Page
Catalog NumberDY521-05
Quantity1 Kit (for 5 Plates)
ApplicationsELISA
Detection Range62.50 - 4000 pg/mL
ReactivityRat
Detection TargetIL-18/IL-1F4
StorageStore the unopened product at 2 - 8 °C. Do not use past expiration date
NCBI Full Gene Nameinterleukin 18
NCBI Gene AliasesIL-1 gamma, IL-18

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Disulfiram attenuates immobilization-induced knee joint contracture by suppressing Caspase-1/GSDMD-mediated pyroptosisScientific ReportsMarch 9, 2026Qian Lu, Xiuli Kan, Quanbing Zhang, Deting Zhu, Zunyu Du, Xueming Li, Han Xiao, Jing Mao, Run Zhang, Yun Zhouenzyme-linked immunosorbent assay (ELISA). IL-1β ELISA kit (R&D Systems, Cat: DY501) and IL-18 ELISA kit (R&D Systems, Cat: DY521-05) were used according to the manufacturer’s instructions. Briefly, standards and samples were added to

(2) Renal denervation attenuates cardiac dysfunction in HFpEF by inhibiting the ATP-P2X7-NLRP3 inflammasome axisBasic Research in CardiologySeptember 16, 2025Zhuqing Li, Xiaoqiang Sun, Yanxin Wang, Feng Zhang, Li Wang, Chunbo Ai, Xu Zhang, Xuemei Yin, Chunlei Liu, Chao Li, et al.conditioned medium from H9c2 cells and primary NRCMs was collected for the determination of cytokines IL18 (DY521-05, R&D Systems, Minneapolis, MN, USA), IL-1β (RLB00, R&D Systems, Minneapolis, MN, USA), IL-6 (ab234570,

(3) Electroacupuncture at ST36 Treatment Suppresses the Microglial Pyroptosis Through Activating α7nAChR in a Rat Model of Asphyxial Cardiac ArrestJ Inflamm ResJuly 2, 2025Yuan Qin, Gangguo Ma, Xiao Xiao, Yongfei Liu, Zhaoyan Zhao, Fang Zhao, Fei Guo, Shuang Wang, Xude Sun, Changjun Gaocytokines interleukin-1β (IL-1β, R&D Systems, RLB00-1, USA) and interleukin-18 (IL-18, R&D Systems, DY521-05, USA) in the brain tissues or the cells culture supernatant following the different treatments were

(4) Kaempferol inhibits cardiomyocyte pyroptosis via promoting O-GlcNAcylation of GSDME and improved acute myocardial infarctionBMC pharmacology & toxicologyApril 8, 2025Zhou J, Zhou H, Zhu J, Fang S.

(5) NLRP3 Inflammasome Activation Is Involved in Geniposide-Induced HepatotoxicityMediators of inflammationJanuary 1, 2025Liu Y, Liu B, Shi M, Ye T, Li H.

(6) Adropin/Tirzepatide Combination Mitigates Cardiac Metabolic Aberrations in a Rat Model of Polycystic Ovarian Syndrome, Implicating the Role of the AKT/GSK3β/NF-κB/NLRP3 PathwayInternational journal of molecular sciencesDecember 24, 2024Hegab II, El-Horany HE, Abd-Ellatif RN, Nasef NA, Okasha AH, Emam MN, Hassan S, Elseady WS, Radwan DA, ElEsawy RO, et al.MyBioSource, Inc., San Diego, CA, USA, catalog # MBS825017; R&D Systems, Inc., Minneapolis, MN, USA, catalog # DY521-05; and MyBioSource, catalog # MBS1600201 and MBS730623, respectively. Cardiac tissue levels of NF-κB,

(7) LDHA exacerbates myocardial ischemia-reperfusion injury through inducing NLRP3 lactylationBMC cardiovascular disordersNovember 16, 2024Fang L, Yu Z, Qian X, Fang H, Wang Y.

(8) Methamphetamine Enhancement of HIV-1 gp120-Mediated NLRP3 Inflammasome Activation and Resultant Proinflammatory Responses in Rat Microglial CulturesInternational journal of molecular sciencesMarch 22, 2024Dutta D, Liu J, Xu E, Xiong H.Cytokines in supernatants were detected using the ELISA kit (Cat# DY501 for IL-1β, DY510 for TNFα, DY521-05 for IL-18, and DY506 for IL-6; R&D systems, Inc. Minneapolis, MN, USA). The experiments were performed

(9) Magnetic vagus nerve stimulation alleviates myocardial ischemia-reperfusion injury by the inhibition of pyroptosis through the M2AChR/OGDHL/ROS axis in ratsJournal of NanobiotechnologyNovember 14, 2023Yao Lu, Kaiyan Chen, Wei Zhao, Yan Hua, Siyuan Bao, Jian Zhang, Tianyu Wu, Gaoyuan Ge, Yue Yu, Jianfei Sun, et al.Rat Interleukin 1β (IL-1β) ELISA Kit (CSB-E08055r, CUSABIO, China) and Rat Interleukin 18 (IL-18) ELISA Kit (DY521-05, R&D Systems, USA). Tunel staining Tunel staining was performed using a Tunel detection kit (40307ES50,

(10) Establishment of a Rat Model of Alcoholic Liver Fibrosis with Simulated Human Drinking Patterns and Low-Dose Chemical StimulationBiomoleculesAugust 24, 2023Lin CY, Omoscharka E, Liu Y, Cheng K.

(11) Ameliorative effect of cheqianzi decoction on hyperuricemia and kidney injury and underlying mechanism in ratsHeliyonApril 1, 2023Meng J, Tian J, Zhao Y, Li C, Yi Y, Zhang Y, Han J, Wang L, Pan C, Liu S, et al.

(12) DUSP8/TAK1 signaling mediates neuropathic pain through regulating neuroinflammation and neuron death in a spinal nerve ligation (SNL) rat modelInternational immunopharmacologyDecember 1, 2022Liao C, Zhou H, Chen H, Cheng G, Li S, Ma F, Yang X, Xie B, Zhang W.

(13) Long noncoding RNA X-inactive specific transcript regulates NLR family pyrin domain containing 3/caspase-1-mediated pyroptosis in diabetic nephropathyWorld journal of diabetesApril 15, 2022Xu J, Wang Q, Song YF, Xu XH, Zhu H, Chen PD, Ren YP.cell culture supernatant was collected. The expression levels of interleukin-1β (IL-1β, RLB00) and IL-18 (DY521-05) in renal tissue and cells were determined according to the ELISA kit instructions (R&D Systems, Minneapolis,

(14) HMGA2 Promotes Brain Injury in Rats with Cerebral Infarction by Activating TLR4/NF-κB Signaling PathwayMediators of inflammationJanuary 1, 2022Huang S, Hong Z, Zhang L, Guo J, Li Y, Li K.

(15) Endogenous tRNA-derived small RNA (tRF3-Thr-AGT) inhibits ZBP1/NLRP3 pathway-mediated cell pyroptosis to attenuate acute pancreatitis (AP)Journal of cellular and molecular medicineNovember 1, 2021Sun B, Chen Z, Chi Q, Zhang Y, Gao B.

(16) IP3R1 regulates Ca2+ transport and pyroptosis through the NLRP3/Caspase-1 pathway in myocardial ischemia/reperfusion injuryCell Death DiscoveryJune 1, 2021Guixi Mo, Xin Liu, Yiyue Zhong, Jian Mo, Zhiyi Li, Daheng Li, Liangqing Zhang, Yijun Liudetected according to Rat IL-1β/IL-1F2 Quantikine ELISA kit (RLB00, R&D Systems) and Rat IL-18 ELISA kit (DY521-05, R&D Systems). Statistical analysis Data analysis was introduced using the SPSS 21.0 (IBM Corp., Armonk,

(17) Dexmedetomidine alleviates blunt chest trauma and hemorrhagic shock‑resuscitation‑induced acute lung injury through inhibiting the NLRP3 inflammasomeMolecular medicine reportsSeptember 1, 2020Ming T, Yuan M, Kong Q, Huang Q, Xia Z, Wu X.supernatant fluid was harvested and assayed using ELISA kits (IL-1β, cat. no. RLB00; IL-18, cat. no. DY521-05; IL-6, cat. no. R6000B; TNF-α, cat. no. RTA00; all R&D Systems, Inc.) to measure the levels of proinflammatory

(18) MiR-199a modulates autophagy and inflammation in rats with cerebral infarction via regulating mTOR expressionEuropean review for medical and pharmacological sciencesJune 1, 2020Zhou J, Wu JS, Yan Y, Li J, Ni T, Shao W, Mei JH, Xiong WZ, Wu H.

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IL-18/IL-1F4 ELISA

IL-18/IL-1F4 ELISA

Rat IL-18 DuoSet ELISA from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Rat IL-18 DuoSet ELISA from R&D Systems, a Bio-Techne Brand

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