Fig 1: L-DOPA enhanced maturation and functionality of iRPE cells. A densely packed monolayer of hexagonal, pigmented iRPE cells. Scale bar = 50 μm. B Western blot analysis of RPE maturation markers CRALBP, BEST1, and RPE65. C Examination of iRPE polarity through apical and basal secretion of PEDF and VEGF. D Comparison of TER between control and L-DOPA iRPE. E Comparison of POS phagocytosis between control and L-DOPA iRPE. Scale bar = 20 μm. Data are represented as mean ± SEM, n = 3; statistical analysis was performed using unpaired two-tailed t-tests; *p < 0.05, **p < 0.01, ***p < 0.001, ns: not significant