Fig 1: Protein levels of Glypicans and Notum determined by ELISA kit at 0, 7, 14 and 21 days of BM-MSC and osteoblast culture in patients with Osteoarthritis (n = 8) and controls (n = 8). T-tests were used to compare the groups: * p < 0.05, ** p < 0.01, *** p < 0.001. All bar graphs are presented as mean ± SEM. In OA BM-MSCs, a decrease in GPC5 and Notum and an increase in GPC3 were found. During osteogenic differentiation, a decrease in GPC2, GPC5 and Notum and an increase in GPC3 were observed in OA patients. GPC1, GPC4 and GPC6 were not found in soluble form.
Fig 2: Plasma levels of Glypicans and Notum in patients with Osteoarthritis (n = 25) and controls (n = 24). Non-parametric Mann–Whitney test (GPC2, GPC4, GPC6 and Notum) and t-test (GPC1, GPC5, GPC3) were used to compare the groups: * p < 0.05. All bar graphs are presented as mean ± SEM. A decrease in GPC5 and Notum were found in OA patients.
Supplier Page from Thermo Fisher Scientific for Human Glypican 1 ELISA Kit