Fig 1: General condition and changes in the duodenum of dextran sulphate sodium (DSS)-treated mice. (A) Weight loss after DSS treatment; mean ± 95% CI. (B) Colon shortening after DSS treatment; mean ± SD; one-way ANOVA with post hoc test. (C–F) Cross-sections of the duodenum; periodic acid Schiff reaction. (C)—Tie-Cre, control group; (D)—PPIA×Tie-Cre, control group; (E)—Tie-Cre, DSS; (F)—PPIA×Tie-Cre, DSS. 1—villus. 2—crypt. 3—region of lymphoplasmacytic infiltration. 4—swelling of the lamina propria. Black arrows—goblet cells; red arrows—Paneth cells. Blue arrows denote structures with corresponding digits. Scale bar: 100 µm. (G,H) The mean number of goblet cells per villus and Paneth cells per crypt in the duodenum; two-way ANOVA with Šídák’s post hoc test. * p < 0.05, **** p < 0.0001, ns or # p > 0.05.