TissueSpec® Multi-Organ Metastasis dECM Kit from Xylyx Bio

Metastasis is the main cause of death from cancer. The extracellular matrix (ECM) is essential for regulating tumor cell migration away from the primary tumor and invasion at distant sites. The In Site™ Metastasis Kit includes minimally-processed, decellularized extracellular matrix (dECM) biomaterials derived from common sites for cancer colonization—bone, liver, and lung tissues—that allow researchers to gain insights into the complex interactions between tumor cells and their microenvironment.

This application note highlights the advantages of incorporating the In Site™ Metastasis Kit into tumor models including the ability to recapitulate common metastatic microenvironments, to evaluate drug response of tumors in physiologically-relevant models, and to identify mechanisms of tumor drug resistance. Read More