Fig 1: Graphical representation of cyclic AMP response element binding protein (CREB) level in different brain regionsA) Hippocampal level of CREB was significantly (***P<0.001) increased in MK-80+datumetine mice than Veh and datumetine mice.B) PFC level of CREB was increased in Datumetine mice while MK-801+datumetine mice showed reduced CREB than Veh, though no significant difference was observed.C) Cerebellar CREB level was reduced in all treated mice compared to Veh mice, though not significant.