Description
Transmembrane proteins take on various biological functions and play an important role in the occurrence and development of disease. Membrane protein sample preparation needs to take full account of the downstream applications, such as gel analysis and mass spectrometry analysis, so the preparation of membrane protein samples become an insurmountable challenge. Conventional methods of preparing membrane protein samples are solubilization using detergents and surfactants. Detergent treatment will make the membrane protein loss of its natural structure, thus hindering the functional study of membrane proteins