Fig 1: Analysis in aqueous humor samples of selected dysregulated proteins by ELISA. A) ELISA and ROC curves analyses of RAD23B levels in aqueous humor samples from ICL (N = 28) individuals, and cataracts (N = 28) and glaucoma (N = 24) patients showed significantly lower RAD23B protein levels in glaucoma aqueous humor samples than in ICL and cataracts samples, with a diagnostic ability higher than 70 % to discriminate glaucoma patients from ICL individuals and of 68.90 % to discriminate glaucoma patients from cataracts patients. B) The combination of RAD23B with previously identified SPP1 and GAS6 glaucoma biomarkers increased RAD23B diagnostic ability of glaucoma up to 83 %, with a sensitivity higher than 79 %, and specificity higher than 65 %.
Fig 2: Analysis in aqueous humor samples of selected dysregulated proteins by ELISA. A) ELISA and ROC curves analyses of RAD23B levels in aqueous humor samples from ICL (N = 28) individuals, and cataracts (N = 28) and glaucoma (N = 24) patients showed significantly lower RAD23B protein levels in glaucoma aqueous humor samples than in ICL and cataracts samples, with a diagnostic ability higher than 70 % to discriminate glaucoma patients from ICL individuals and of 68.90 % to discriminate glaucoma patients from cataracts patients. B) The combination of RAD23B with previously identified SPP1 and GAS6 glaucoma biomarkers increased RAD23B diagnostic ability of glaucoma up to 83 %, with a sensitivity higher than 79 %, and specificity higher than 65 %.
Supplier Page from Biorbyt for Human RAD23B ELISA Kit
Application Notes: tissue homogenates and other biological fluids.