Fig 2: (A) Multiplying DKK1 with sAxl values was more associated with HCC compared to each marker alone. (B) As reported form the area under receiver-operating characteristic curve this model enhances the diagnostic power for HCC detection. P<0.50 is considered significant.

Fig 3: Elevated DKK1×sAxl Values were Associated with HCC Aggressiveness Including (A) multiple nodules, (B) large size and (C) Child and (D) BCLC late stages. P<0.50 is considered significant.

Fig 4: (A) Multiplying DKK1 with sAxl values was more associated with HCC compared to each marker alone. (B) As reported form the area under receiver-operating characteristic curve this model enhances the diagnostic power for HCC detection. P<0.50 is considered significant.

Fig 5: (A) DKK1 and (B) sAxl was associated with HCC development and their levels were increase with disease progression. The area under receiver-operating characteristic curve of (C) DKK1 and (D) sAxl revealed that both were had a good ability to discriminate patients with HCC from non-HCC patients (liver fibrosis and cirrhosis combined). P<0.50 is considered significant.